OBJECTIVE: To assess the utility of abdominal scintigraphy with 99mTc-HMPAO labelled leukocytes in the diagnosis of infectious complications of continuous ambulatory peritoneal dialysis (CAPD). MATERIAL AND METHODS: 17 patients in CAPD were evaluated (35 studies). They were divided into three groups: group control in asymptomathic patients (5), group of studies in patients with suspicion of exit site infection/catheter tunnel (18) and group of studies in patients with clinical suspicion of peritonitis (12). All patients underwent abdominal scintigraphy with 99mTc-HMPAO labelled leukocytes. The results were compared to final clinical diagnosis, assessing the exit site or dialysis liquid external aspect, material or exit site secretion culture and clinical follow up. RESULTS: In the case studied, we obtained high sensitivity and specificity values for the exit site infection diagnosis (83 % and 75 % respectively), and a sensitivity of 100 % in the diagnosis of peritonitis as well. We detected a case of catheter tunnel infection confirmed by culture. No pathological uptake was observed in any control case. CONCLUSIONS: Abdominal scintigraphy with 99mTc-HMPAO labelled leukocytes allows the early diagnosis of infectious complications of CAPD, and the control of treatment response, avoiding its unnecessary prolongation.
OBJECTIVE: To assess the utility of abdominal scintigraphy with 99mTc-HMPAO labelled leukocytes in the diagnosis of infectious complications of continuous ambulatory peritoneal dialysis (CAPD). MATERIAL AND METHODS: 17 patients in CAPD were evaluated (35 studies). They were divided into three groups: group control in asymptomathic patients (5), group of studies in patients with suspicion of exit site infection/catheter tunnel (18) and group of studies in patients with clinical suspicion of peritonitis (12). All patients underwent abdominal scintigraphy with 99mTc-HMPAO labelled leukocytes. The results were compared to final clinical diagnosis, assessing the exit site or dialysis liquid external aspect, material or exit site secretion culture and clinical follow up. RESULTS: In the case studied, we obtained high sensitivity and specificity values for the exit site infection diagnosis (83 % and 75 % respectively), and a sensitivity of 100 % in the diagnosis of peritonitis as well. We detected a case of catheter tunnel infection confirmed by culture. No pathological uptake was observed in any control case. CONCLUSIONS: Abdominal scintigraphy with 99mTc-HMPAO labelled leukocytes allows the early diagnosis of infectious complications of CAPD, and the control of treatment response, avoiding its unnecessary prolongation.