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Literature DB >> 15625021

The evolving role of spinal agents in acute pain.

Abstract

Local anesthetics and opioids were among the earliest pharmacologic agents used for intrathecal injection. Side-effect profiles have limited the use of additional agents and, after a century of clinical use, local anesthetics and opioids remain the most widely used intrathecal or epidural medications.

Entities: Disease

Mesh：

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Year: 2005 PMID： 15625021 DOI： 10.1007/s11916-005-0070-z

Source DB: PubMed Journal: Curr Pain Headache Rep ISSN： 1534-3081

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References

48 in total

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Journal: Anesthesiology Date: 1999-06 Impact factor: 7.892

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Authors: K H Gwirtz; J V Young; R S Byers; C Alley; K Levin; S G Walker; R K Stoelting
Journal: Anesth Analg Date: 1999-03 Impact factor: 5.108

The evolving role of spinal agents in acute pain.

1. Postoperative analgesia by intraarticular and epidural neostigmine following knee surgery.

2. Spinal anesthesia with meperidine. Effects of added alpha-adrenergic agonists: epinephrine versus clonidine.

3. Study of three different doses of epidural neostigmine coadministered with lidocaine for postoperative analgesia.

Review 4. The neurotoxicity of drugs given intrathecally (spinal)

5. The safety and efficacy of intrathecal opioid analgesia for acute postoperative pain: seven years' experience with 5969 surgical patients at Indiana University Hospital.

6. Epidural ketamine potentiates epidural morphine but not fentanyl in acute nociception in rats.

7. Epidural neostigmine produces analgesia but also sedation in women after cesarean delivery.

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