Literature DB >> 15624998

New synthesis of benzothiazines and benzoisothiazoles containing a sulfoximine functional group.

Michael Harmata1, Kanok-On Rayanil, Maria G Gomes, Pinguan Zheng, Nathan L Calkins, Soo-Yeun Kim, Yimin Fan, Valentina Bumbu, Dong Reyoul Lee, Sumrit Wacharasindhu, Xuechuan Hong.   

Abstract

The reaction of S-2-bromophenyl-S-methylsulfoximine with terminal alkynes in the presence of a palladium catalyst resulted in the formation of both 1,2-benzothiazines and 1,2-benzoisothiazoles. A preference for the former was seen with alkylalkynes, while the latter were preferentially formed with alkynylarenes.

Entities:  

Year:  2005        PMID： 15624998     DOI： 10.1021/ol047781j

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Preparation of S-2-halophenyl-2,1-benzothiazines.

Authors:  Aswin Garimalla; Michael Harmata
Journal:  Tetrahedron       Date:  2021-02-10       Impact factor: 2.457

2.  A Direct and an Efficient Regioselective Synthesis of 1,2-Benzothiazine 1,1-dioxides, β-Carbolinones, Indolo[2,3-c]pyran-1-ones, Indolo[3,2-c]pyran-1-ones, Thieno[2,3-c]pyran-7-ones and Pyrano[3',4':4,5]imidazo[1,2-a]pyridin-1-ones via Tandem Stille/Heterocyclization Reaction.

Authors:  Badr Jismy; Khalil Cherry; Carine Maaliki; Samuel Inack Ngi; Mohamed Abarbri
Journal:  Molecules       Date:  2020-11-04       Impact factor: 4.411
  2 in total

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