| Literature DB >> 15624992 |
Todd A Davis1, Pramod R Chopade, Göran Hilmersson, Robert A Flowers.
Abstract
Reduction of a series of beta-hydroxyketones by SmI2/H2O/Et3N provided 1,3-diols in quantitative yields. The reactions were exceedingly clean with no byproduct formation, negating the need for further purification. Most reactions provided moderate to excellent diastereoselectivity with syn-diols as the major isomer in most instances.Entities:
Year: 2005 PMID： 15624992 DOI： 10.1021/ol047835p
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005