Literature DB >> 15624959

Copper-free sonogashira coupling reaction with PdCl2 in water under aerobic conditions.

Bo Liang1, Mingji Dai, Jiahua Chen, Zhen Yang.   

Abstract

A mild protocol for the copper-free Sonogashira coupling of aryl iodides with terminal acetylenes in water under aerobic conditions has been developed. The use of 1 mol % PdCl(2) in the presence of pyrrolidine allows the coupling reaction to proceed at room temperature or 50 degrees C with good to excellent yields.

Entities:  

Year:  2005        PMID： 15624959     DOI： 10.1021/jo048599z

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  7 in total

Review 1.  Acetylene-based materials in organic photovoltaics.

Authors:  Fabio Silvestri; Assunta Marrocchi
Journal:  Int J Mol Sci       Date:  2010-04-08       Impact factor: 5.923

2.  Au(I)/Au(III)-catalyzed Sonogashira-type reactions of functionalized terminal alkynes with arylboronic acids under mild conditions.

Authors:  Deyun Qian; Junliang Zhang
Journal:  Beilstein J Org Chem       Date:  2011-06-15       Impact factor: 2.883

3.  Practical synthesis of aryl-2-methyl-3-butyn-2-ols from aryl bromides via conventional and decarboxylative copper-free Sonogashira coupling reactions.

Authors:  Andrea Caporale; Stefano Tartaggia; Andrea Castellin; Ottorino De Lucchi
Journal:  Beilstein J Org Chem       Date:  2014-02-12       Impact factor: 2.883

4.  Design, synthesis and evaluation of novel 2,2-dimethyl-2,3-dihydroquinolin-4(1H)-one based chalcones as cytotoxic agents.

Authors:  Julie Jean; David S Farrell; Angela M Farrelly; Sinead Toomey; James W Barlow
Journal:  Heliyon       Date:  2018-09-04

5.  A Mild Aqueous Sonogashira Reaction as a Fluorescent Labeling Strategy for 5-Bromide-2'-Deoxyuridine.

Authors:  Shufang Wang; Yongxin Gao; Shigang Shen; Hui Wen; Huaqing Cui
Journal:  Molecules       Date:  2018-01-12       Impact factor: 4.411

6.  Greener Biogenic Approach for the Synthesis of Palladium Nanoparticles Using Papaya Peel: An Eco-Friendly Catalyst for C-C Coupling Reaction.

Authors:  Anindita Dewan; Manashi Sarmah; Ashim J Thakur; Pankaj Bharali; Utpal Bora
Journal:  ACS Omega       Date:  2018-05-17

Review 7.  Pd-Catalyzed Cross-Couplings: On the Importance of the Catalyst Quantity Descriptors, mol % and ppm.

Authors:  Christopher S Horbaczewskyj; Ian J S Fairlamb
Journal:  Org Process Res Dev       Date:  2022-07-11       Impact factor: 3.858
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.