Literature DB >> 15623711

Neurofibrillary tangles in ALS and Parkinsonism-dementia complex focus in Kii, Japan.

Yasumasa Kokubo1, Shigeki Kuzuhara.   

Abstract

Brains of 41 residents without neurodegenerative diseases in the high-incidence area of ALS/parkinsonism-dementia complex (ALS/PDC) of the Kii Peninsula of Japan were neuropathologically examined. Neurofibrillary tangles (NFTs) in the hippocampal area were present in 11 of the 41 cases, but the frequency of NFT-positive cases in each age group was similar to that of the normal Japanese population and far less than that of Guamanians without ALS/PDC.

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Year:  2004        PMID: 15623711     DOI: 10.1212/01.wnl.0000147241.52694.6a

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  6 in total

1.  An Assessment of Possible Neuropathology and Clinical Relationships in 46 Sporadic Amyotrophic Lateral Sclerosis Patient Autopsies.

Authors:  Grant Coan; Cassie S Mitchell
Journal:  Neurodegener Dis       Date:  2015-07-16       Impact factor: 2.977

Review 2.  The neuropathological signature of bulbar-onset ALS: A systematic review.

Authors:  S Shellikeri; V Karthikeyan; R Martino; S E Black; L Zinman; J Keith; Y Yunusova
Journal:  Neurosci Biobehav Rev       Date:  2017-02-02       Impact factor: 8.989

3.  ALS-Plus syndrome: non-pyramidal features in a large ALS cohort.

Authors:  Leo McCluskey; Shannon Vandriel; Lauren Elman; Vivianna M Van Deerlin; John Powers; Ashley Boller; Elisabeth McCarty Wood; John Woo; Corey T McMillan; Katya Rascovsky; Murray Grossman
Journal:  J Neurol Sci       Date:  2014-07-18       Impact factor: 3.181

4.  Nitrative Stress and Tau Accumulation in Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex (ALS/PDC) in the Kii Peninsula, Japan.

Authors:  Yukiko Hata; Ning Ma; Misao Yoneda; Satoru Morimoto; Hideyuki Okano; Shigeo Murayama; Shosuke Kawanishi; Shigeki Kuzuhara; Yasumasa Kokubo
Journal:  Front Neurosci       Date:  2018-01-22       Impact factor: 4.677

5.  Evolvability of Amyloidogenic Proteins in Human Brain.

Authors:  Makoto Hashimoto; Gilbert Ho; Shuei Sugama; Yoshiki Takamatsu; Yuka Shimizu; Takato Takenouchi; Masaaki Waragai; Eliezer Masliah
Journal:  J Alzheimers Dis       Date:  2018       Impact factor: 4.472

6.  Brain Transcriptome Analysis Links Deficiencies of Stress-Responsive Proteins to the Pathomechanism of Kii ALS/PDC.

Authors:  Satoru Morimoto; Mitsuru Ishikawa; Hirotaka Watanabe; Miho Isoda; Masaki Takao; Shiho Nakamura; Fumiko Ozawa; Yoshifumi Hirokawa; Shigeki Kuzuhara; Hideyuki Okano; Yasumasa Kokubo
Journal:  Antioxidants (Basel)       Date:  2020-05-14
  6 in total

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