Literature DB >> 15621284

Synthesis, characterization, DNA-binding and photocleavage studies of [Ru(bpy)2(PPIP)]2+ and [Ru(phen)2(PPIP)]2+.

Li-Feng Tan1, Hui Chao, Hong Li, Yun-Jun Liu, Bin Sun, Wei Wei, Liang-Nian Ji.   

Abstract

A novel ligand 2-(4'-phenoxy-phenyl)imidazo[4,5-f][1,10]phenanthroline (PPIP) and its complexes [Ru(bpy)(2)(PPIP)](2+) (1) (bpy = 2,2'-bipyridine) and [Ru(phen)(2)(PPIP)](2+) (2) (phen = 1,10-phenanthroline) have been synthesized and characterized by mass spectroscopy, (1)H NMR and cyclic voltammetry. The interaction of two complexes with calf thymus DNA (CT-DNA) was investigated by spectroscopic and viscosity measurements. The results suggest that both complexes bind to DNA via an intercalative mode. Both complexes have also been found to promote the photocleavage of plasmid pBR 322 DNA under irradiated.

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Year:  2005        PMID： 15621284     DOI： 10.1016/j.jinorgbio.2004.10.028

Source DB:  PubMed          Journal:  J Inorg Biochem        ISSN： 0162-0134            Impact factor:   4.155


  12 in total

1.  DNA studies of newly synthesized heteroleptic platinum(II) complexes [Pt(bpy)(iip)](2+) and [Pt(bpy)(miip)](2.).

Authors:  Burak Coban; Ishak Ozel Tekin; Abdurrahman Sengul; Ufuk Yildiz; Izzet Kocak; Nergis Sevinc
Journal:  J Biol Inorg Chem       Date:  2015-12-01       Impact factor: 3.358

Review 2.  Correlation Between Molecular Modelling and Spectroscopic Techniques in Investigation With DNA Binding Interaction of Ruthenium(II) Complexes.

Authors:  B Thulasiram; C Shobha Devi; Yata Praveen Kumar; Rajeshwar Rao Aerva; S Satyanarayana; Penumaka Nagababu
Journal:  J Fluoresc       Date:  2016-12-06       Impact factor: 2.217

3.  Synthesis, characterization, and DNA binding of complexes [Pt(bpy)(pip)](2+) and [Pt(bpy)(hpip)] (2+).

Authors:  Burak Coban; Ufuk Yildiz; Abdurrahman Sengul
Journal:  J Biol Inorg Chem       Date:  2013-03-14       Impact factor: 3.358

Review 4.  Analytical Techniques Used to Detect DNA Binding Modes of Ruthenium(II) Complexes with Extended Phenanthroline Ring.

Authors:  C Shobha Devi; B Thulasiram; S Satyanarayana; Penumaka Nagababu
Journal:  J Fluoresc       Date:  2017-08-22       Impact factor: 2.217

5.  Chiral ruthenium(II) anthraquinone complexes as dual inhibitors of topoisomerases I and II.

Authors:  Jun-Feng Kou; Chen Qian; Jin-Quan Wang; Xiang Chen; Li-Li Wang; Hui Chao; Liang-Nian Ji
Journal:  J Biol Inorg Chem       Date:  2011-08-21       Impact factor: 3.358

6.  Synthesis and Characterization of Ru(II) Complexes with π-Expansive Imidazophen Ligands for the Photokilling of Human Melanoma Cells.

Authors:  Goutam Ghosh; Huimin Yin; Susan M A Monro; Tariq Sainuddin; Lloyd Lapoot; Alexander Greer; Sherri A McFarland
Journal:  Photochem Photobiol       Date:  2020-01-09       Impact factor: 3.421

7.  Os(II) Oligothienyl Complexes as a Hypoxia-Active Photosensitizer Class for Photodynamic Therapy.

Authors:  John A Roque; Patrick C Barrett; Houston D Cole; Liubov M Lifshits; Evan Bradner; Ge Shi; David von Dohlen; Susy Kim; Nino Russo; Gagan Deep; Colin G Cameron; Marta E Alberto; Sherri A McFarland
Journal:  Inorg Chem       Date:  2020-10-30       Impact factor: 5.165

8.  Synthesis, characterization, DNA binding studies, photocleavage, cytotoxicity and docking studies of ruthenium(II) light switch complexes.

Authors:  Nazar Mohammed Gabra; Bakheit Mustafa; Yata Praveen Kumar; C Shobha Devi; A Srishailam; P Venkat Reddy; Kotha Laxma Reddy; S Satyanarayana
Journal:  J Fluoresc       Date:  2013-08-28       Impact factor: 2.217

9.  Targeting topoisomerase II with the chiral DNA-intercalating ruthenium(II) polypyridyl complexes.

Authors:  Feng Gao; Hui Chao; Jin-Quan Wang; Yi-Xian Yuan; Bin Sun; Yuan-Fang Wei; Bin Peng; Liang-Nian Ji
Journal:  J Biol Inorg Chem       Date:  2007-07-21       Impact factor: 3.358

10.  Bis(2,2'-bipyridyl-κ(2)N,N')dichlorido-rhodium(III) perchlorate.

Authors:  Alla Dikhtiarenko; Laura Torre-Fernández; Santiago García-Granda; José R García; José Gimeno
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-05-02
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