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Literature DB >> 15620635

Notch signaling: a different sort makes the cut.

Abstract

Notch signaling is regulated by ubiquitination of the receptor and its extracellular ligands. New studies reveal distinct ubiquitination-dependent endosomal sorting pathways in which ligand-bound Notch is activated while unliganded Notch is recycled or degraded, facilitating signaling while preventing inappropriate activation of unstimulated receptors.

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Year: 2004 PMID： 15620635 DOI： 10.1016/j.cub.2004.11.041

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

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Cited

15 in total

1. Identification of novel cell-adhesion molecules in peripheral nerves using a signal-sequence trap.

Authors: Ivo Spiegel; Konstantin Adamsky; Menahem Eisenbach; Yael Eshed; Adrian Spiegel; Rhona Mirsky; Steven S Scherer; Elior Peles
Journal: Neuron Glia Biol Date: 2006-02

2. Delta-like 1-Lysine613 regulates notch signaling.

Authors: Liguo Zhang; Ryan C Widau; B Paul Herring; Patricia J Gallagher
Journal: Biochim Biophys Acta Date: 2011-10-02

3. Mammalian NOTCH Receptor Activation and Signaling Protocols.

Authors: María-Luisa Nueda; Victoriano Baladrón
Journal: Methods Mol Biol Date: 2022

4. Activation of Notch-mediated protective signaling in the myocardium.

Authors: Natalie A Gude; Gregory Emmanuel; Weitao Wu; Christopher T Cottage; Kimberlee Fischer; Pearl Quijada; John A Muraski; Roberto Alvarez; Marta Rubio; Eric Schaefer; Mark A Sussman
Journal: Circ Res Date: 2008-03-27 Impact factor: 17.367

5. Effect of presenilins in the apoptosis of thymocytes and homeostasis of CD8+ T cells.

Authors: Antonio Maraver; Carlos E Tadokoro; Michelle L Badura; Jie Shen; Manuel Serrano; Juan J Lafaille
Journal: Blood Date: 2007-07-12 Impact factor: 22.113

6. The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer.

Authors: Alessandra Rustighi; Luca Tiberi; Alessia Soldano; Marco Napoli; Paolo Nuciforo; Antonio Rosato; Fred Kaplan; Anthony Capobianco; Salvatore Pece; Pier Paolo Di Fiore; Giannino Del Sal
Journal: Nat Cell Biol Date: 2009-01-18 Impact factor: 28.824

Notch signaling: a different sort makes the cut.

1. Identification of novel cell-adhesion molecules in peripheral nerves using a signal-sequence trap.

2. Delta-like 1-Lysine613 regulates notch signaling.

3. Mammalian NOTCH Receptor Activation and Signaling Protocols.

4. Activation of Notch-mediated protective signaling in the myocardium.

5. Effect of presenilins in the apoptosis of thymocytes and homeostasis of CD8+ T cells.

6. The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer.

Review 7. Endocytosis and intracellular trafficking of Notch and its ligands.

8. Notch post-translationally regulates β-catenin protein in stem and progenitor cells.

Review 9. Regulation of cell proliferation and differentiation in the kidney.

Review 10. Ubiquitination and Deubiquitination in Oral Disease.