| Literature DB >> 15620634 |
Kimberly A Burns1, Fabio Martinon.
Abstract
Many patients with Crohn's disease carry mutations in NOD2, a molecule that can both activate and attenuate the pro-inflammatory effects of NF-kappa B. Recent studies implicate NOD2-induced ubiquitination of the NF-kappa B regulator NEMO as a potential means of manipulating the NF-kappa B signal.Entities:
Mesh：
Substances：
Year: 2004 PMID： 15620634 DOI： 10.1016/j.cub.2004.11.040
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834