Literature DB >> 15620259

Novel cytotoxic thiodiketopiperazine derivatives from a Tilachlidium sp.

Yunjiang Feng1, John W Blunt, Anthony L J Cole, Murray H G Munro.   

Abstract

Three novel thiodiketopiperazine derivatives, T988 A, B, and C (1-3), were isolated from a Tilachlidium sp. Their structures were elucidated by spectroscopic analyses using various 1D and 2D NMR techniques. All the compounds showed potent cytotoxicity against cultured P388 leukemia cells.

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Year:  2004        PMID： 15620259     DOI： 10.1021/np030326w

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  14 in total

1.  Antimicrobial Potential of Thiodiketopiperazine Derivatives Produced by Phoma sp., an Endophyte of Glycyrrhiza glabra Linn.

Authors:  Palak Arora; Zahoor A Wani; Yedukondalu Nalli; Asif Ali; Syed Riyaz-Ul-Hassan
Journal:  Microb Ecol       Date:  2016-06-29       Impact factor: 4.552

2.  Cytotoxic epipolythiodioxopiperazine alkaloids from filamentous fungi of the Bionectriaceae.

Authors:  Mario Figueroa; Tyler N Graf; Sloan Ayers; Audrey F Adcock; David J Kroll; Jilai Yang; Steven M Swanson; Ulyana Munoz-Acuna; Esperanza J Carcache de Blanco; Rajesh Agrawal; Mansukh C Wani; Blaise A Darveaux; Cedric J Pearce; Nicholas H Oberlies
Journal:  J Antibiot (Tokyo)       Date:  2012-09-12       Impact factor: 2.649

3.  Enantioselective total synthesis of (+)-gliocladin C.

Authors:  Larry E Overman; Youseung Shin
Journal:  Org Lett       Date:  2007-01-18       Impact factor: 6.005

4.  Generic concepts in Nectriaceae.

Authors:  L Lombard; N A van der Merwe; J Z Groenewald; P W Crous
Journal:  Stud Mycol       Date:  2015-01-29       Impact factor: 16.097

5.  Enantioselective total syntheses of plectosphaeroic acids B and C.

Authors:  Salman Y Jabri; Larry E Overman
Journal:  J Org Chem       Date:  2013-08-27       Impact factor: 4.354

Review 6.  Epidithiodioxopiperazines. occurrence, synthesis and biogenesis.

Authors:  Timothy R Welch; Robert M Williams
Journal:  Nat Prod Rep       Date:  2014-10       Impact factor: 13.423

7.  Enantioselective total synthesis of plectosphaeroic acid B.

Authors:  Salman Y Jabri; Larry E Overman
Journal:  J Am Chem Soc       Date:  2013-03-06       Impact factor: 15.419

8.  General approach for preparing epidithiodioxopiperazines from trioxopiperazine precursors: enantioselective total syntheses of (+)- and (-)-gliocladine C, (+)-leptosin D, (+)-T988C, (+)-bionectin A, and (+)-gliocladin A.

Authors:  John E DeLorbe; David Horne; Richard Jove; Steven M Mennen; Sangkil Nam; Fang-Li Zhang; Larry E Overman
Journal:  J Am Chem Soc       Date:  2013-03-01       Impact factor: 15.419

9.  Concise Total Synthesis of (+)-Gliocladins B and C.

Authors:  Nicolas Boyer; Mohammad Movassaghi
Journal:  Chem Sci       Date:  2012-03-30       Impact factor: 9.825

10.  Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids.

Authors:  Nicolas Boyer; Karen C Morrison; Justin Kim; Paul J Hergenrother; Mohammad Movassaghi
Journal:  Chem Sci       Date:  2013-04-01       Impact factor: 9.825
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