| Literature DB >> 15619510 |
Abstract
Praziquantel is the current drug of choice for the control of schistosomiasis. It is highly effective against all species of schistosomes and shows minimal adverse effects. Though introduced for the treatment of schistosomiasis more than 20 years ago, the mode of action of praziquantel remains to be elucidated. This review will focus on advances in defining the molecular target of praziquantel action, with particular emphasis on recent work indicating an important role for voltage-gated calcium channels.Entities:
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Year: 2004 PMID： 15619510 DOI： 10.1016/j.ijpara.2004.09.004
Source DB: PubMed Journal: Int J Parasitol ISSN： 0020-7519 Impact factor: 3.981