Literature DB >> 15619185

Current treatment of pediatric empyema.

John A Hawkins1, Eric S Scaife, Neal D Hillman, G Peter Feola.   

Abstract

Pneumonia with complicated parapneumonic effusion and empyema is increasing in incidence and continues to be a source of morbidity in children seen in our institution. Current diagnostic modalities include chest radiographs and CT scanning with ultrasound being helpful in some situations. Exact management of empyema remains controversial. Although open thoracotomy drainage is well accepted in children, video-assisted thoracoscopic surgery (VATS) drainage has become more prevalent in the current era. Over the last 4 years, we have treated 58 children with intrapleural placement of pigtail catheters and administration fibrinolytics consisting of tissue plasminogen activator (tPA). Successful drainage and resolution of 54 of the 58 effusions was achieved with percutaneous methods alone. There was no mortality or 30-day recurrence. Mean hospital stay was 9.1 days (range 5 to 21) and mean chest catheter removal was 6 days post placement (range 1.5 to 20). Of the four patients that failed percutaneous tube therapy, 3 underwent video assisted thoracic surgery (VATS), and one had open thoracotomy with decortication. Based on our experience, tPA administered through a small bore chest tube for drainage of complicated parapneumonic effusions has become our standard practice. We reserve VATS for treatment failures and open thoracotomy and decortication for patients with VATS failure.

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Year:  2004        PMID: 15619185     DOI: 10.1053/j.semtcvs.2004.08.004

Source DB:  PubMed          Journal:  Semin Thorac Cardiovasc Surg        ISSN: 1043-0679


  9 in total

1.  Management of parapneumonic empyema.

Authors:  Krow Ampofo; Carrie Byington
Journal:  Pediatr Infect Dis J       Date:  2007-05       Impact factor: 2.129

2.  The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America.

Authors:  John S Bradley; Carrie L Byington; Samir S Shah; Brian Alverson; Edward R Carter; Christopher Harrison; Sheldon L Kaplan; Sharon E Mace; George H McCracken; Matthew R Moore; Shawn D St Peter; Jana A Stockwell; Jack T Swanson
Journal:  Clin Infect Dis       Date:  2011-08-31       Impact factor: 9.079

3.  Quality improvement guidelines for pediatric abscess and fluid drainage.

Authors:  Mark J Hogan; Francis E Marshalleck; Manrita K Sidhu; Bairbre L Connolly; Richard B Towbin; Wael A Saad; Ann Marie Cahill; John Crowley; Manraj K S Heran; Eric J Hohenwalter; Derek J Roebuck; Michael J Temple; T Gregory Walker; John F Cardella
Journal:  Pediatr Radiol       Date:  2012-11-02

4.  Less is best? The impact of urokinase as the first line management of empyema thoracis.

Authors:  B A Khalil; P A Corbett; M O Jones; C T Baillie; Kevin Southern; P D Losty; S E Kenny
Journal:  Pediatr Surg Int       Date:  2006-09-30       Impact factor: 1.827

5.  Stratifying fibrinolytic dosing in pediatric parapneumonic effusion based on ultrasound grade correlation.

Authors:  Charles A James; Leah E Braswell; Amir H Pezeshkmehr; Paula K Roberson; James A Parks; Mary B Moore
Journal:  Pediatr Radiol       Date:  2016-10-05

6.  Retrospective analysis of large-dose intrapleural alteplase for complicated pediatric parapneumonic effusion and empyema.

Authors:  Jessica L Taylor; Meixia Liu; David S Hoff
Journal:  J Pediatr Pharmacol Ther       Date:  2015 Mar-Apr

7.  Complicated parapneumonic effusion and empyema: pleural decortication and video-assisted thoracic surgery.

Authors:  Shi-Ping Luh; Gwo-Jong Hsu; Chen Cheng-Ren
Journal:  Curr Infect Dis Rep       Date:  2008-05       Impact factor: 3.725

8.  Alteplase: pleural effusion (parapneumonic) and empyema in children.

Authors:  Joyce A Generali; Dennis J Cada
Journal:  Hosp Pharm       Date:  2013-12

9.  Efficacy of standardizing fibrinolytic therapy for parapneumonic effusion.

Authors:  Charles A James; P Spencer Lewis; Mary B Moore; Kevin Wong; Emily K Rader; Paula K Roberson; Nancy A Ghaleb; Hanna K Jensen; Amir H Pezeshkmehr; Michael H Stroud; Daniel J Ashton
Journal:  Pediatr Radiol       Date:  2022-04-22
  9 in total

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