Literature DB >> 15618703

CYPalleles: a web page for nomenclature of human cytochrome P450 alleles.

Mikael Oscarson1, Magnus Ingelman-Sundberg.   

Abstract

Genetic variations in the genes encoding the cytochrome P450s (CYPs) are important determinants for interindividual differences in sensitivity to drugs and environmental chemicals as well as for the pathogenesis of several human diseases. In order to standardise the nomenclature of the rapidly increasing number of alleles described, a web page was established a few years ago. Here, we describe the present status of the web page and summarise the principles used for CYP allele nomenclature.

Entities:  

Year:  2002        PMID: 15618703     DOI: 10.2133/dmpk.17.491

Source DB:  PubMed          Journal:  Drug Metab Pharmacokinet        ISSN: 1347-4367            Impact factor:   3.614


  6 in total

1.  Free energies of binding of R- and S-propranolol to wild-type and F483A mutant cytochrome P450 2D6 from molecular dynamics simulations.

Authors:  Chris de Graaf; Chris Oostenbrink; Peter H J Keizers; Barbara M A van Vugt-Lussenburg; Jan N M Commandeur; Nico P E Vermeulen
Journal:  Eur Biophys J       Date:  2007-02-27       Impact factor: 1.733

Review 2.  Databases in the area of pharmacogenetics.

Authors:  Sarah C Sim; Russ B Altman; Magnus Ingelman-Sundberg
Journal:  Hum Mutat       Date:  2011-04-05       Impact factor: 4.878

3.  The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database.

Authors:  Andrea Gaedigk; Magnus Ingelman-Sundberg; Neil A Miller; J Steven Leeder; Michelle Whirl-Carrillo; Teri E Klein
Journal:  Clin Pharmacol Ther       Date:  2017-11-14       Impact factor: 6.875

4.  The cytochrome P450 engineering database: Integration of biochemical properties.

Authors:  Demet Sirim; Florian Wagner; Andrey Lisitsa; Jürgen Pleiss
Journal:  BMC Biochem       Date:  2009-11-12       Impact factor: 4.059

5.  Meta-analysis and pooled analysis of GSTM1 and CYP1A1 polymorphisms and oral and pharyngeal cancers: a HuGE-GSEC review.

Authors:  Leonor Varela-Lema; Emanuela Taioli; Alberto Ruano-Ravina; Juan M Barros-Dios; Devasena Anantharaman; Simone Benhamou; Stefania Boccia; Rajani A Bhisey; Gabriella Cadoni; Ettore Capoluongo; Chien-Jen Chen; William Foulkes; Eny Maria Goloni-Bertollo; Ana Hatagima; Richard B Hayes; Takahiko Katoh; Sergio Koifman; Phillip Lazarus; Johannes J Manni; Manoj Mahimkar; Shunji Morita; Jong Park; Kwang-Kyun Park; Erika Cristina Pavarino Bertelli; Enilze Maria de Souza Fonseca Ribeiro; Bidyut Roy; Margaret R Spitz; Richard C Strange; Qingyi Wei; Camille C Ragin
Journal:  Genet Med       Date:  2008-06       Impact factor: 8.822

6.  MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect.

Authors:  Daniel Esposito; Jochen Weile; Jay Shendure; Lea M Starita; Anthony T Papenfuss; Frederick P Roth; Douglas M Fowler; Alan F Rubin
Journal:  Genome Biol       Date:  2019-11-04       Impact factor: 13.583

  6 in total

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