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Literature DB >> 15618213

Tissue inhibitor of metalloproteinase 1 regulates resistance to infection.

Marie Mei Lee¹, Bong-June Yoon, Keith Osiewicz, Michael Preston, Brian Bundy, Anna M van Heeckeren, Zena Werb, Paul D Soloway.

Abstract

Tissue inhibitor of metalloproteinase 1 (TIMP-1)-deficient mice are resistant to Pseudomonas aeruginosa corneal infections. Corneas healed completely in TIMP-1-deficient mice, and infections were cleared faster in TIMP-1-deficient mice than in wild-type littermates. Genetic suppression studies using matrix metalloproteinase (MMP)-deficient mice showed that MMP-9, MMP-3, and MMP-7 but not MMP-2 or MMP-12 are needed for resistance. Increased resistance was also seen during pulmonary infections. These results identify a novel pathway regulating infection resistance.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2005 PMID： 15618213 PMCID： PMC538985 DOI： 10.1128/IAI.73.1.661-665.2005

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

35 in total

1. MMPs and TIMPs. An historical perspective.

Authors: J F Woessner
Journal: Methods Mol Biol Date: 2001

2. Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury.

Authors: Qinglang Li; Pyong Woo Park; Carole L Wilson; William C Parks
Journal: Cell Date: 2002-11-27 Impact factor: 41.582

3. Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense.

Authors: C L Wilson; A J Ouellette; D P Satchell; T Ayabe; Y S López-Boado; J L Stratman; S J Hultgren; L M Matrisian; W C Parks
Journal: Science Date: 1999-10-01 Impact factor: 47.728

4. Evidence for TIMP-1 protection against P. aeruginosa-induced corneal ulceration and perforation.

Authors: K A Kernacki; R Barrett; L D Hazlett
Journal: Invest Ophthalmol Vis Sci Date: 1999-12 Impact factor: 4.799

5. TIMP-1 promotes VEGF-induced neovascularization in the retina.

Authors: E Yamada; T Tobe; H Yamada; N Okamoto; D J Zack; Z Werb; P D Soloway; P A Campochiaro
Journal: Histol Histopathol Date: 2001-01 Impact factor: 2.303

6. Interstitial fibrosis in mice with overload proteinuria: deficiency of TIMP-1 is not protective.

Authors: A A Eddy; H Kim; J López-Guisa; T Oda; P D Soloway
Journal: Kidney Int Date: 2000-08 Impact factor: 10.612

7. Regulation of MMPs and TIMPs by IL-1beta during corneal ulceration and infection.

Authors: Mei Lang Xue; Denis Wakefield; Mark D P Willcox; Andrew R Lloyd; Nick Di Girolamo; Nerida Cole; Archana Thakur
Journal: Invest Ophthalmol Vis Sci Date: 2003-05 Impact factor: 4.799

8. Abnormal TNF activity in Timp3-/- mice leads to chronic hepatic inflammation and failure of liver regeneration.

Authors: Fazilat F Mohammed; David S Smookler; Suzanne E M Taylor; Barbara Fingleton; Zamaneh Kassiri; Otto H Sanchez; Jane L English; Lynn M Matrisian; Billie Au; Wen-Chen Yeh; Rama Khokha
Journal: Nat Genet Date: 2004-08-22 Impact factor: 38.330

9. Threonine 98, the pivotal residue of tissue inhibitor of metalloproteinases (TIMP)-1 in metalloproteinase recognition.

Authors: Meng-Huee Lee; Magdalini Rapti; Vera Knaüper; Gillian Murphy
Journal: J Biol Chem Date: 2004-01-20 Impact factor: 5.157

10. The effects of dexamethasone in vitro on the production of collagenase and inhibitor by synovial and cartilage explants from the joints of rabbits with a proliferative arthritis.

Authors: G J Cambray; G Murphy; J J Reynolds
Journal: Rheumatol Int Date: 1981 Impact factor: 2.631

20 in total

1. Persistent macrophage/microglial activation and myelin disruption after experimental autoimmune encephalomyelitis in tissue inhibitor of metalloproteinase-1-deficient mice.

Authors: Stephen J Crocker; Jason K Whitmire; Ricardo F Frausto; Parntip Chertboonmuang; Paul D Soloway; J Lindsay Whitton; Iain L Campbell
Journal: Am J Pathol Date: 2006-12 Impact factor: 4.307

Review 2. Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted.

Authors: Kendra J Greenlee; Zena Werb; Farrah Kheradmand
Journal: Physiol Rev Date: 2007-01 Impact factor: 37.312

Review 3. Matrix metalloproteinases and the regulation of tissue remodelling.

Authors: Andrea Page-McCaw; Andrew J Ewald; Zena Werb
Journal: Nat Rev Mol Cell Biol Date: 2007-03 Impact factor: 94.444

Review 4. The tissue inhibitors of metalloproteinases (TIMPs): an ancient family with structural and functional diversity.

Authors: Keith Brew; Hideaki Nagase
Journal: Biochim Biophys Acta Date: 2010-01-15

5. Role for matrix metalloproteinase 9 in granuloma formation during pulmonary Mycobacterium tuberculosis infection.

Authors: Jennifer L Taylor; Jessica M Hattle; Steven A Dreitz; JoLynn M Troudt; Linda S Izzo; Randall J Basaraba; Ian M Orme; Lynn M Matrisian; Angelo A Izzo
Journal: Infect Immun Date: 2006-09-18 Impact factor: 3.441

6. Astrocytic tissue inhibitor of metalloproteinase-1 (TIMP-1) promotes oligodendrocyte differentiation and enhances CNS myelination.

Authors: Craig S Moore; Richard Milner; Akiko Nishiyama; Ricardo F Frausto; David R Serwanski; Roberto R Pagarigan; J Lindsay Whitton; Robert H Miller; Stephen J Crocker
Journal: J Neurosci Date: 2011-04-20 Impact factor: 6.167