Literature DB >> 15618212

Relative contributions of innate and acquired host responses to bacterial control and arthritis development in Lyme disease.

Xiaohui Wang1, Ying Ma, John H Weis, James F Zachary, Carsten J Kirschning, Janis J Weis.   

Abstract

TLR2(-/-)/scid double-mutant mice were infected with B. burgdorferi to assess the relative importance of acquired and innate host defenses. Although spirochete levels at 4 weeks were lower in TLR2(-/-) mice than in TLR2(-/-)/scid mice, the increased arthritis severity of TLR2 (Toll-like receptor 2)-deficient mice was reduced by the presence of the scid mutation.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 15618212      PMCID： PMC538980          DOI： 10.1128/IAI.73.1.657-660.2005

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  36 in total

1.  Clearance of Borrelia burgdorferi may not be required for resistance to experimental lyme arthritis.

Authors:  C R Brown; S L Reiner
Journal:  Infect Immun       Date:  1998-05       Impact factor: 3.441

Review 2.  Lyme disease.

Authors:  J J Nocton; A C Steere
Journal:  Adv Intern Med       Date:  1995

3.  Protective and arthritis-resolving activity in sera of mice infected with Borrelia burgdorferi.

Authors:  S W Barthold; S Feng; L K Bockenstedt; E Fikrig; K Feen
Journal:  Clin Infect Dis       Date:  1997-07       Impact factor: 9.079

4.  Genetic control of experimental lyme arthritis in the absence of specific immunity.

Authors:  C R Brown; S L Reiner
Journal:  Infect Immun       Date:  1999-04       Impact factor: 3.441

5.  Modulation of murine Lyme borreliosis by interruption of the B7/CD28 T-cell costimulatory pathway.

Authors:  M C Shanafelt; I Kang; S W Barthold; L K Bockenstedt
Journal:  Infect Immun       Date:  1998-01       Impact factor: 3.441

6.  Distinct characteristics of resistance to Borrelia burgdorferi-induced arthritis in C57BL/6N mice.

Authors:  Y Ma; K P Seiler; E J Eichwald; J H Weis; C Teuscher; J J Weis
Journal:  Infect Immun       Date:  1998-01       Impact factor: 3.441

7.  Serum-mediated resolution of Lyme arthritis in mice.

Authors:  S W Barthold; M deSouza; S Feng
Journal:  Lab Invest       Date:  1996-01       Impact factor: 5.662

8.  Effect of anti-interleukin 12 treatment on murine lyme borreliosis.

Authors:  J Anguita; D H Persing; M Rincon; S W Barthold; E Fikrig
Journal:  J Clin Invest       Date:  1996-02-15       Impact factor: 14.808

9.  Identification of quantitative trait loci governing arthritis severity and humoral responses in the murine model of Lyme disease.

Authors:  J J Weis; B A McCracken; Y Ma; D Fairbairn; R J Roper; T B Morrison; J H Weis; J F Zachary; R W Doerge; C Teuscher
Journal:  J Immunol       Date:  1999-01-15       Impact factor: 5.422

10.  T helper phenotype and genetic susceptibility in experimental Lyme disease.

Authors:  J E Matyniak; S L Reiner
Journal:  J Exp Med       Date:  1995-03-01       Impact factor: 14.307
View more
  19 in total

Review 1.  Lyme arthritis: current concepts and a change in paradigm.

Authors:  Dean T Nardelli; Steven M Callister; Ronald F Schell
Journal:  Clin Vaccine Immunol       Date:  2007-11-14

2.  Macrophage p38 mitogen-activated protein kinase activity regulates invariant natural killer T-cell responses during Borrelia burgdorferi infection.

Authors:  Kelly Hawley; Nicolás Navasa; Chris M Olson; Tonya C Bates; Renu Garg; Michael N Hedrick; Dietrich Conze; Mercedes Rincón; Juan Anguita
Journal:  J Infect Dis       Date:  2012-05-02       Impact factor: 5.226

3.  Association of a Toll-like receptor 1 polymorphism with heightened Th1 inflammatory responses and antibiotic-refractory Lyme arthritis.

Authors:  Klemen Strle; Junghee J Shin; Lisa J Glickstein; Allen C Steere
Journal:  Arthritis Rheum       Date:  2012-05

4.  Bioluminescent imaging of Borrelia burgdorferi in vivo demonstrates that the fibronectin-binding protein BBK32 is required for optimal infectivity.

Authors:  Jenny A Hyde; Eric H Weening; Mihee Chang; Jerome P Trzeciakowski; Magnus Höök; Jeffrey D Cirillo; Jon T Skare
Journal:  Mol Microbiol       Date:  2011-08-30       Impact factor: 3.501

5.  Dual role of MyD88 in rapid clearance of relapsing fever Borrelia spp.

Authors:  Devin D Bolz; Rhianna S Sundsbak; Ying Ma; Shizuo Akira; John H Weis; Tom G Schwan; Janis J Weis
Journal:  Infect Immun       Date:  2006-10-09       Impact factor: 3.441

6.  BB0323 function is essential for Borrelia burgdorferi virulence and persistence through tick-rodent transmission cycle.

Authors:  Xinyue Zhang; Xiuli Yang; Manish Kumar; Utpal Pal
Journal:  J Infect Dis       Date:  2009-10-15       Impact factor: 5.226

Review 7.  Gene expression profiling provides insights into the pathways involved in inflammatory arthritis development: murine model of Lyme disease.

Authors:  Jennifer C Miller; Ying Ma; Hillary Crandall; Xiaohui Wang; Janis J Weis
Journal:  Exp Mol Pathol       Date:  2008-04-08       Impact factor: 3.362

8.  Distinct roles for MyD88 and Toll-like receptors 2, 5, and 9 in phagocytosis of Borrelia burgdorferi and cytokine induction.

Authors:  Ok S Shin; Ralph R Isberg; Shizuo Akira; Satoshi Uematsu; Aruna K Behera; Linden T Hu
Journal:  Infect Immun       Date:  2008-03-31       Impact factor: 3.441

9.  Non-anticoagulant Heparin as a Pre-exposure Prophylaxis Prevents Lyme Disease Infection.

Authors:  Yi-Pin Lin; Yanlei Yu; Ashley L Marcinkiewicz; Patricia Lederman; Thomas M Hart; Fuming Zhang; Robert J Linhardt
Journal:  ACS Infect Dis       Date:  2020-01-30       Impact factor: 5.084

10.  A chromosomally encoded virulence factor protects the Lyme disease pathogen against host-adaptive immunity.

Authors:  Xiuli Yang; Adam S Coleman; Juan Anguita; Utpal Pal
Journal:  PLoS Pathog       Date:  2009-03-06       Impact factor: 6.823
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.