Literature DB >> 15616327

In vivo resistance of a laboratory-selected Aspergillus fumigatus isolate to amphotericin B.

Elias K Manavathu1, Jessica L Cutright, Pranatharthi H Chandrasekar.   

Abstract

The fungal burdens (number of CFU per pair of lungs) in mice infected with Aspergillus fumigatus AB16.4 (for which the amphotericin B [AMB] MIC was elevated) and W73355 (drug-susceptible parent) were reduced by 21 and 81%, respectively, after 5 days of AMB treatment (2 mg/kg/day), indicating that AB16.4 also shows reduced susceptibility to AMB in a murine pulmonary aspergillosis model.

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Year:  2005        PMID： 15616327      PMCID： PMC538856          DOI： 10.1128/AAC.49.1.428-430.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  6 in total

1.  Efficacy of LY303366 against amphotericin B-susceptible and -resistant Aspergillus fumigatus in a murine model of invasive aspergillosis.

Authors:  P E Verweij; K L Oakley; J Morrissey; G Morrissey; D W Denning
Journal:  Antimicrob Agents Chemother       Date:  1998-04       Impact factor: 5.191

2.  Evaluation of possible correlations between antifungal susceptibilities of filamentous fungi in vitro and antifungal treatment outcomes in animal infection models.

Authors:  F C Odds; F Van Gerven; A Espinel-Ingroff; M S Bartlett; M A Ghannoum; M V Lancaster; M A Pfaller; J H Rex; M G Rinaldi; T J Walsh
Journal:  Antimicrob Agents Chemother       Date:  1998-02       Impact factor: 5.191

3.  Lack of correlation of in vitro amphotericin B susceptibility testing with outcome in a murine model of Aspergillus infection.

Authors:  E M Johnson; K L Oakley; S A Radford; C B Moore; P Warn; D W Warnock; D W Denning
Journal:  J Antimicrob Chemother       Date:  2000-01       Impact factor: 5.790

4.  In-vitro and in-vivo susceptibility of Aspergillus fumigatus to a novel conjugated styryl ketone.

Authors:  E K Manavathu; J R Dimmock; S C Vashishtha; J Cutright; P H Chandrasekar
Journal:  J Antimicrob Chemother       Date:  1998-11       Impact factor: 5.790

5.  In-vitro isolation and antifungal susceptibility of amphotericin B-resistant mutants of Aspergillus fumigatus.

Authors:  E K Manavathu; G J Alangaden; P H Chandrasekar
Journal:  J Antimicrob Chemother       Date:  1998-06       Impact factor: 5.790

6.  In-vitro testing of susceptibility to amphotericin B is a reliable predictor of clinical outcome in invasive aspergillosis.

Authors:  C Lass-Flörl; G Kofler; G Kropshofer; J Hermans; A Kreczy; M P Dierich; D Niederwieser
Journal:  J Antimicrob Chemother       Date:  1998-10       Impact factor: 5.790
  6 in total
  2 in total

1.  Avian Aspergillus fumigatus strains resistant to both itraconazole and voriconazole.

Authors:  L A Beernaert; F Pasmans; L Van Waeyenberghe; G M Dorrestein; F Verstappen; F Vercammen; F Haesebrouck; A Martel
Journal:  Antimicrob Agents Chemother       Date:  2009-03-02       Impact factor: 5.191

Review 2.  Role and Interpretation of Antifungal Susceptibility Testing for the Management of Invasive Fungal Infections.

Authors:  Frederic Lamoth; Russell E Lewis; Dimitrios P Kontoyiannis
Journal:  J Fungi (Basel)       Date:  2020-12-30
  2 in total

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