Literature DB >> 15616176

One-year change in cerebral glucose metabolism in patients with Alzheimer's disease.

Nobutsugu Hirono1, Mamoru Hashimoto, Kazunari Ishii, Hiroaki Kazui, Etsuro Mori.   

Abstract

By using [(18)F]-2-fluoro-deoxy-d-glucose and positron emission tomography, the authors studied changes in regional glucose metabolism after a 1-year interval in patients with mild Alzheimer's disease (AD). Glucose metabolism declined over time in the bilateral precuneus and posterior cingulate gyri and in the frontal, temporal, and parietal cortices. Glucose metabolism in these regions may be a useful measure of the progression of AD and a valid surrogate outcome measure of clinical drug trials.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15616176     DOI： 10.1176/jnp.16.4.488

Source DB:  PubMed          Journal:  J Neuropsychiatry Clin Neurosci        ISSN： 0895-0172            Impact factor:   2.198


  8 in total

Review 1.  Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives.

Authors:  Harald Hampel; Richard Frank; Karl Broich; Stefan J Teipel; Russell G Katz; John Hardy; Karl Herholz; Arun L W Bokde; Frank Jessen; Yvonne C Hoessler; Wendy R Sanhai; Henrik Zetterberg; Janet Woodcock; Kaj Blennow
Journal:  Nat Rev Drug Discov       Date:  2010-07       Impact factor: 84.694

Review 2.  Neuronal AChE splice variants and their non-hydrolytic functions: redefining a target of AChE inhibitors?

Authors:  M Zimmermann
Journal:  Br J Pharmacol       Date:  2013-11       Impact factor: 8.739

3.  White matter pathology isolates the hippocampal formation in Alzheimer's disease.

Authors:  D H Salat; D S Tuch; A J W van der Kouwe; D N Greve; V Pappu; S Y Lee; N D Hevelone; A K Zaleta; J H Growdon; S Corkin; B Fischl; H D Rosas
Journal:  Neurobiol Aging       Date:  2010-02       Impact factor: 4.673

4.  Quantitative analysis of the effects of donepezil on regional cerebral blood flow in Alzheimer's disease by using an automated program, 3DSRT.

Authors:  Masaru Tateno; Seiju Kobayashi; Kumiko Utsumi; Hidetoshi Morii; Kazuki Fujii
Journal:  Neuroradiology       Date:  2008-05-16       Impact factor: 2.804

5.  Alzheimer's-type neuropathology in the precuneus is not increased relative to other areas of neocortex across a range of cognitive impairment.

Authors:  Peter T Nelson; Erin L Abner; Stephen W Scheff; Frederick A Schmitt; Richard J Kryscio; Gregory A Jicha; Charles D Smith; Ela Patel; William R Markesbery
Journal:  Neurosci Lett       Date:  2008-11-08       Impact factor: 3.046

6.  Attention-Related Brain Activation Is Altered in Older Adults With White Matter Hyperintensities Using Multi-Echo fMRI.

Authors:  Sarah Atwi; Arron W S Metcalfe; Andrew D Robertson; Jeremy Rezmovitz; Nicole D Anderson; Bradley J MacIntosh
Journal:  Front Neurosci       Date:  2018-10-18       Impact factor: 4.677

7.  Donepezil in Alzheimer's disease: From conventional trials to pharmacogenetics.

Authors:  Ramón Cacabelos
Journal:  Neuropsychiatr Dis Treat       Date:  2007-06       Impact factor: 2.570

8.  Biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's disease.

Authors:  Chera L Maarouf; Tyler A Kokjohn; Douglas G Walker; Charisse M Whiteside; Walter M Kalback; Alexis Whetzel; Lucia I Sue; Geidy Serrano; Sandra A Jacobson; Marwan N Sabbagh; Eric M Reiman; Thomas G Beach; Alex E Roher
Journal:  PLoS One       Date:  2014-08-28       Impact factor: 3.240
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.