OBJECTIVE: The purpose of our study was to describe the high-resolution CT and pathologic findings of giant cell interstitial pneumonia (GIP) in four adult patients. CONCLUSION: GIP appears on high-resolution CT as ground-glass and irregular linear opacities in both lungs. These CT findings correspond histopathologically to areas of interstitial thickening caused by fibrosis and inflammatory cell infiltration and to areas of intraalveolar accumulation of macrophages and multinucleated giant cells.
OBJECTIVE: The purpose of our study was to describe the high-resolution CT and pathologic findings of giant cell interstitial pneumonia (GIP) in four adult patients. CONCLUSION: GIP appears on high-resolution CT as ground-glass and irregular linear opacities in both lungs. These CT findings correspond histopathologically to areas of interstitial thickening caused by fibrosis and inflammatory cell infiltration and to areas of intraalveolar accumulation of macrophages and multinucleated giant cells.
Authors: J Chiarchiaro; L R Tomsic; S Strock; K L Veraldi; M Nouraie; J Sellares; K O Lindell; L A Ortiz; F C Sciurba; R F Kucera; S A Yousem; C R Fuhrman; D J Kass; K F Gibson Journal: Respir Med Case Rep Date: 2018-08-10