Literature DB >> 15614600

[Cognitive dysfunction after abdominal surgery in elderly patients].

S V Müller1, N Krause, M Schmidt, T F Münte, S Münte.   

Abstract

Elderly patients often suffer from postoperative cognitive deficits (POCD) after serious surgical operations. The reasons for this are not well understood. We investigated the influence of the invasiveness of the operation and the duration of the operation as well as the patient's preoperative physical status on measures of cognitive dysfunction. In a prospective study 59 elderly patients (mean age 69.2 years) were subjected to a neuropsychological test battery and a questionnaire following an abdominal surgical operation. The postoperative recovery with a focus on memory function was assessed using the Wechsler Memory Scale (WMS) seven days after the operation. Self-reported cognitive deficits were studied using the a questionnaire of experienced attention deficits (FEDA) three months after the operation. Postoperative psychological and self-reported test results varied as a function of the invasiveness and the duration of the operation. After more invasive operations patients reported a stronger deficit in activities of daily living and a reduction in drive than after less invasive operations. In addition, the duration of anesthesia influenced the experienced deficits. The self-reported deficits were more strongly influenced by the features of the operation than the psychological test data. The physical status of the patients according to the American Society of Anesthesiologists (ASA) along with the duration of anesthesia as covariate was identified as a good predictor for the cognitive recovery post operation.

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Year:  2004        PMID: 15614600     DOI: 10.1007/s00391-004-0212-7

Source DB:  PubMed          Journal:  Z Gerontol Geriatr        ISSN: 0948-6704            Impact factor:   1.281


  32 in total

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3.  Age and other risk factors for neuropsychologic decline in patients undergoing coronary artery bypass graft surgery.

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Review 10.  Defining neuropsychological dysfunction after coronary artery bypass grafting.

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Journal:  Ann Thorac Surg       Date:  1996-05       Impact factor: 4.330

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  5 in total

1.  Postoperative cognitive dysfunction: computerized and conventional tests showed only moderate inter-rater reliability.

Authors:  Finn M Radtke; Martin Franck; Norbert Papkalla; Tim S Herbig; Edith Weiss-Gerlach; Robin Kleinwaechter; Klaus D Wernecke; Claudia D Spies
Journal:  J Anesth       Date:  2010-05-28       Impact factor: 2.078

Review 2.  [Delirium in the elderly].

Authors:  Manfred Gogol
Journal:  Z Gerontol Geriatr       Date:  2008-10-30       Impact factor: 1.281

3.  How to prevent perioperative delirium in the elderly?

Authors:  Simone Gurlit; Michael Möllmann
Journal:  Z Gerontol Geriatr       Date:  2008-10-30       Impact factor: 1.281

Review 4.  Hyperbaric oxygen preconditioning improves postoperative cognitive dysfunction by reducing oxidant stress and inflammation.

Authors:  Zhi-Xin Gao; Jin Rao; Yuan-Hai Li
Journal:  Neural Regen Res       Date:  2017-02       Impact factor: 5.135

5.  Acetylcholinesterase inhibitors reduce neuroinflammation and -degeneration in the cortex and hippocampus of a surgery stress rat model.

Authors:  Alexander Kalb; Clarissa von Haefen; Marco Sifringer; Annalena Tegethoff; Nadine Paeschke; Mariya Kostova; Aarne Feldheiser; Claudia D Spies
Journal:  PLoS One       Date:  2013-05-03       Impact factor: 3.240

  5 in total

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