Literature DB >> 15614521

Recent developments in the management of invasive fungal infections in patients with hematological malignancies.

Meinolf Karthaus1, Oliver A Cornely.   

Abstract

Despite recent advances in the last decade, invasive fungal infections are still associated with a high morbidity and mortality. Invasive fungal infections constitute severe infectious complications in patients with hematological malignancies receiving myelosuppressive chemotherapy or sustained immunosuppression after allogeneic transplant regimens. Following a long period of stagnation, considerable progress has been made during the last 5 years in non-culture-based diagnostics and in the treatment of invasive fungal infections. This review highlights recent developments in the epidemiology, diagnosis, and treatment in the context of state-of-the-art management of invasive fungal infections in cancer patients.

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Year:  2004        PMID: 15614521     DOI: 10.1007/s00277-004-0986-0

Source DB:  PubMed          Journal:  Ann Hematol        ISSN: 0939-5555            Impact factor:   3.673


  5 in total

1.  Incidence and etiology of cerebrovascular disease in patients with malignancy.

Authors:  Jeffrey M Katz; Alan Z Segal
Journal:  Curr Atheroscler Rep       Date:  2005-07       Impact factor: 5.967

2.  Single-ascending-dose pharmacokinetics and safety of the novel broad-spectrum antifungal triazole BAL4815 after intravenous infusions (50, 100, and 200 milligrams) and oral administrations (100, 200, and 400 milligrams) of its prodrug, BAL8557, in healthy volunteers.

Authors:  Anne Schmitt-Hoffmann; Brigitte Roos; Markus Heep; Michael Schleimer; Erhard Weidekamm; Tom Brown; Michael Roehrle; Christoph Beglinger
Journal:  Antimicrob Agents Chemother       Date:  2006-01       Impact factor: 5.938

3.  Multiple-dose pharmacokinetics and safety of the new antifungal triazole BAL4815 after intravenous infusion and oral administration of its prodrug, BAL8557, in healthy volunteers.

Authors:  Anne Schmitt-Hoffmann; Brigitte Roos; Jürgen Maares; Markus Heep; Jochen Spickerman; Erhard Weidekamm; Tom Brown; Michael Roehrle
Journal:  Antimicrob Agents Chemother       Date:  2006-01       Impact factor: 5.938

4.  Invasive fungal infections in neutropenic enterocolitis: a systematic analysis of pathogens, incidence, treatment and mortality in adult patients.

Authors:  Marcus Gorschlüter; Ulrich Mey; John Strehl; Volker Schmitz; Christian Rabe; Katharina Pauls; Carsten Ziske; Ingo G H Schmidt-Wolf; Axel Glasmacher
Journal:  BMC Infect Dis       Date:  2006-02-26       Impact factor: 3.090

5.  Treatment of invasive fungal infections in clinical practice: a multi-centre survey on customary dosing, treatment indications, efficacy and safety of voriconazole.

Authors:  Jörg J Vehreschild; Angelika Böhme; Dietmar Reichert; Michael G Kiehl; Dorothee Arenz; Karen Pankraz; Matthias Kochanek; Andrew J Ullmann; Oliver A Cornely
Journal:  Int J Hematol       Date:  2008-02-21       Impact factor: 2.490

  5 in total

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