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Literature DB >> 15614382

NMR and ion selective electrode studies of hydraphile channels correlate with biological activity in E. coli and B. subtilis.

W Matthew Leevy¹, Michelle E Weber, Paul H Schlesinger, George W Gokel.

Abstract

Previous sodium ion transport results obtained by NMR methods are compared with those obtained by a new ISE technique and are found to correlate well with each other and with the biological activity against E. coli and B. subtilis.

Entities: Chemical Species

Mesh：

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Year: 2004 PMID： 15614382 PMCID： PMC2615580 DOI： 10.1039/b413588a

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

8 in total

1. Hydraphile channels: models for transmembrane, cation-conducting transporters.

Authors: G W Gokel; R Ferdani; J Liu; R Pajewski; H Shabany; P Uetrecht
Journal: Chemistry Date: 2001-01-05 Impact factor: 5.236

2. Antibacterial agents based on the cyclic D,L-alpha-peptide architecture.

Authors: S Fernandez-Lopez; H S Kim; E C Choi; M Delgado; J R Granja; A Khasanov; K Kraehenbuehl; G Long; D A Weinberger; K M Wilcoxen; M R Ghadiri
Journal: Nature Date: 2001-07-26 Impact factor: 49.962

3. The structure of the potassium channel: molecular basis of K+ conduction and selectivity.

Authors: D A Doyle; J Morais Cabral; R A Pfuetzner; A Kuo; J M Gulbis; S L Cohen; B T Chait; R MacKinnon
Journal: Science Date: 1998-04-03 Impact factor: 47.728

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Journal: Annu Rev Biophys Biomol Struct Date: 1995

5. Colorimetric determination of phospholipids with ammonium ferrothiocyanate.

Authors: J C Stewart
Journal: Anal Biochem Date: 1980-05-01 Impact factor: 3.365

6. Membrane destabilization assay based on potassium release from liposomes.

Authors: A Silberstein; T Mirzabekov; W F Anderson; Y Rozenberg
Journal: Biochim Biophys Acta Date: 1999-11-09

7. Synthetic hydraphile channels of appropriate length kill Escherichia coli.

Authors: W Matthew Leevy; Gina M Donato; Riccardo Ferdani; William E Goldman; Paul H Schlesinger; George W Gokel
Journal: J Am Chem Soc Date: 2002-08-07 Impact factor: 15.419

8. Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation.

Authors: F Szoka; D Papahadjopoulos
Journal: Proc Natl Acad Sci U S A Date: 1978-09 Impact factor: 11.205

8 in total

10 in total

1. Recent Advances in Synthetic Membrane Transporters.

Authors: Beth A McNally; W Matthew Leevy; Bradley D Smith
Journal: Supramol Chem Date: 2007-01 Impact factor: 1.688

2. Structure-activity relationships, kinetics, selectivity, and mechanistic studies of synthetic hydraphile channels in bacterial and mammalian cells.

Authors: W Matthew Leevy; Seth T Gammon; Tatiana Levchenko; David D Daranciang; Oscar Murillo; Vladimir Torchilin; David Piwnica-Worms; James E Huettner; George W Gokel
Journal: Org Biomol Chem Date: 2005-08-26 Impact factor: 3.876

3. Activity of synthetic ion channels is influenced by cation-pi interactions with phospholipid headgroups.

Authors: Michelle E Weber; Elizabeth K Elliott; George W Gokel
Journal: Org Biomol Chem Date: 2005-11-30 Impact factor: 3.876

4. Coordination and transport of alkali metal cations through phospholipid bilayer membranes by hydraphile channels.

Authors: George W Gokel; Megan Michele Daschbach
Journal: Coord Chem Rev Date: 2008-04 Impact factor: 22.315

5. Synthetic cation transporters incorporating crown ethers and calixarenes as headgroups and central relays: a comparison of sodium and chloride selectivity.

Authors: José Carlos Iglesias-Sánchez; Wei Wang; Riccardo Ferdani; Pilar Prados; Javier de Mendoza; George W Gokel
Journal: New J Chem Date: 2008 Impact factor: 3.591

6. The influence of aromatic residues in hydraphile spacer units: assay by ion selective electrode methods and in bacteria.

Authors: Adam E Meyer; W Matthew Leevy; Robert Pajewski; Iwao Suzuki; Michelle E Weber; George W Gokel
Journal: Bioorg Med Chem Date: 2005-05-02 Impact factor: 3.641

7. In vivo optical imaging of acute cell death using a near-infrared fluorescent zinc-dipicolylamine probe.

Authors: Bryan A Smith; Seth T Gammon; Shuzhang Xiao; Wei Wang; Sarah Chapman; Ryan McDermott; Mark A Suckow; James R Johnson; David Piwnica-Worms; George W Gokel; Bradley D Smith; W Matthew Leevy
Journal: Mol Pharm Date: 2011-03-01 Impact factor: 4.939