Literature DB >> 15612762

Evaluation of metal and microbial contamination in botanical supplements.

Priyadarshini Raman1, Lina C Patino, Muraleedharan G Nair.   

Abstract

The sale of botanical dietary supplements in the United States is on the rise. However, limited studies have been conducted on the safety of these supplements. There are reports on the presence of undesired metals in some of the botanical dietary supplements. In this study, echinacea, garlic, ginkgo, ginseng, grape seed extract, kava kava, saw palmetto, and St. John's wort supplements manufactured by Nature's Way, Meijer, GNC, Nutrilite, Solaray, Sundown and Natrol, have been analyzed for lead, mercury, cadmium, arsenic, uranium, chromium, vanadium, copper, zinc, molybdenum, palladium, tin, antimony, thallium, and tungsten using inductively coupled plasma mass spectrometry. All samples were devoid of mercury contamination. Results indicated that the botanical supplements analyzed did not contain unacceptable concentrations of these metals. These supplements were also evaluated for microbial contamination, and most samples analyzed showed the presence of bacteria or fungi or both. Microbes were not counted nor were microbial counts determined in these samples.

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Year:  2004        PMID: 15612762     DOI: 10.1021/jf049150+

Source DB:  PubMed          Journal:  J Agric Food Chem        ISSN: 0021-8561            Impact factor:   5.279


  16 in total

1.  Safety, tolerability, and immunologic effects of a food allergy herbal formula in food allergic individuals: a randomized, double-blinded, placebo-controlled, dose escalation, phase 1 study.

Authors:  Julie Wang; Sangita P Patil; Nan Yang; Jimmy Ko; Joohee Lee; Sally Noone; Hugh A Sampson; Xiu-Min Li
Journal:  Ann Allergy Asthma Immunol       Date:  2010-07       Impact factor: 6.347

Review 2.  The role of quality assurance and standardization in the safety of botanical dietary supplements.

Authors:  Richard B van Breemen; Harry H S Fong; Norman R Farnsworth
Journal:  Chem Res Toxicol       Date:  2007-03-16       Impact factor: 3.739

Review 3.  Clinically Relevant Herb-Micronutrient Interactions: When Botanicals, Minerals, and Vitamins Collide.

Authors:  Bill J Gurley; Alyssa Tonsing-Carter; Sheila L Thomas; E Kim Fifer
Journal:  Adv Nutr       Date:  2018-07-01       Impact factor: 8.701

4.  Effect of Antiasthma Simplified Herbal Medicine Intervention on neutrophil predominant airway inflammation in a ragweed sensitized murine asthma model.

Authors:  Kamal D Srivastava; David Dunkin; Changda Liu; Nan Yang; Rachel L Miller; Hugh A Sampson; Xiu-Min Li
Journal:  Ann Allergy Asthma Immunol       Date:  2014-04       Impact factor: 6.347

Review 5.  Metal impurities in food and drugs.

Authors:  Darrell R Abernethy; Anthony J Destefano; Todd L Cecil; Kahkashan Zaidi; Roger L Williams
Journal:  Pharm Res       Date:  2010-03-09       Impact factor: 4.200

6.  Heavy metal and pesticide content in commonly prescribed individual raw Chinese Herbal Medicines.

Authors:  Eric S J Harris; Shugeng Cao; Bruce A Littlefield; Jane A Craycroft; Robert Scholten; Ted Kaptchuk; Yanling Fu; Wenquan Wang; Yong Liu; Hubiao Chen; Zhongzhen Zhao; Jon Clardy; Alan D Woolf; David M Eisenberg
Journal:  Sci Total Environ       Date:  2011-08-06       Impact factor: 7.963

7.  Constituents of the anti-asthma herbal formula ASHMI(TM) synergistically inhibit IL-4 and IL-5 secretion by murine Th2 memory cells, and eotaxin by human lung fibroblasts in vitro.

Authors:  Bolleddula Jayaprakasam; Nan Yang; Ming-Chun Wen; Rong Wang; Joseph Goldfarb; Hugh Sampson; Xiu-Min Li
Journal:  J Integr Med       Date:  2013-05

8.  Herbal supplement use and blood lead levels of United States adults.

Authors:  Catherine Buettner; Kenneth J Mukamal; Paula Gardiner; Roger B Davis; Russell S Phillips; Murray A Mittleman
Journal:  J Gen Intern Med       Date:  2009-07-03       Impact factor: 5.128

9.  Light-enhanced caffeic acid derivatives biosynthesis in hairy root cultures of Echinacea purpurea.

Authors:  Bilal H Abbasi; Chun-Long Tian; Susan J Murch; Praveen K Saxena; Chun-Zhao Liu
Journal:  Plant Cell Rep       Date:  2007-03-30       Impact factor: 4.570

Review 10.  Selection and characterization of botanical natural products for research studies: a NaPDI center recommended approach.

Authors:  Joshua J Kellogg; Mary F Paine; Jeannine S McCune; Nicholas H Oberlies; Nadja B Cech
Journal:  Nat Prod Rep       Date:  2019-08-14       Impact factor: 13.423

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