| Literature DB >> 15610844 |
Abstract
Biologically active, therapeutically useful, DNA binding natural products continue to reveal new paradigms for sequence-selective recognition, to enlist beautiful mechanisms of in situ activation for DNA modification, to define new therapeutic targets, to exploit new mechanisms to achieve cellular selectivity, and to provide a rich source of new drugs. These attributes arise in compact structures of complex integrated function.Mesh:
Substances:
Year: 2004 PMID: 15610844 DOI: 10.1016/j.chembiol.2003.08.012
Source DB: PubMed Journal: Chem Biol ISSN: 1074-5521