Literature DB >> 15610841

The structure of mammalian fatty acid synthase turned back to front.

John E Cronan1.   

Abstract

On page 1667 of this issue, Stuart Smith and colleagues [1] demonstrate that the animal fatty acid synthase is a head-to-head dimer rather than the head-to-tail dimer depicted in textbooks. This has important ramifications for the mechanisms of other multifunctional enzymes such as polyketide synthases [2].

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Year:  2004        PMID: 15610841     DOI: 10.1016/j.chembiol.2004.11.011

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  5 in total

Review 1.  Metabolic genes in cancer: their roles in tumor progression and clinical implications.

Authors:  Eiji Furuta; Hiroshi Okuda; Aya Kobayashi; Kounosuke Watabe
Journal:  Biochim Biophys Acta       Date:  2010-02-01

2.  Novel Structural Components Contribute to the High Thermal Stability of Acyl Carrier Protein from Enterococcus faecalis.

Authors:  Young-Guen Park; Min-Cheol Jung; Heesang Song; Ki-Woong Jeong; Eunjung Bang; Geum-Sook Hwang; Yangmee Kim
Journal:  J Biol Chem       Date:  2015-12-02       Impact factor: 5.157

3.  Bacterial fatty acid synthesis and its relationships with polyketide synthetic pathways.

Authors:  John E Cronan; Jacob Thomas
Journal:  Methods Enzymol       Date:  2009       Impact factor: 1.600

4.  Inefficient translation renders the Enterococcus faecalis fabK enoyl-acyl carrier protein reductase phenotypically cryptic.

Authors:  Hongkai Bi; Lei Zhu; Haihong Wang; John E Cronan
Journal:  J Bacteriol       Date:  2013-10-25       Impact factor: 3.490

Review 5.  Diversity in enoyl-acyl carrier protein reductases.

Authors:  R P Massengo-Tiassé; J E Cronan
Journal:  Cell Mol Life Sci       Date:  2009-05       Impact factor: 9.261

  5 in total

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