Literature DB >> 15608970

[Early functional hemispherectomy in hemimegalencephaly associated to refractory epilepsy].

Luiz Fernando Fonseca1, Renato Pacheco de Melo, Arthur Cukiert, Jose Augusto Burattini, Pedro Paulo Mariani, Ródio Brandão, Lauro Ceda, Cristine Mella Baldauf, Meire Argentoni, Cássio Forster, Carla Baise.   

Abstract

Hemimegalencephaly (HME) is a rare congenital brain malformation of unknown etiology. Patients with HME can present with an early onset epileptic syndrome which is often refractory to medical treatment and associated to impaired neurological development. Functional hemispherectomy (FH) has proven to be a valuable treatment alternative in patients with refractory epilepsy in this setting. Very few children operated under the age of 6 months and bearing HME and catastrophic epilepsy (CE) have been described in the literature. This study reports on 2 kids younger than 6 months with HME and CE submitted to FH with good clinical outcome.

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Year:  2004        PMID: 15608970     DOI: 10.1590/s0004-282x2004000600024

Source DB:  PubMed          Journal:  Arq Neuropsiquiatr        ISSN: 0004-282X            Impact factor:   1.420


  1 in total

Review 1.  Hemimegalencephaly: clinical implications and surgical treatment.

Authors:  C Di Rocco; D Battaglia; D Pietrini; M Piastra; L Massimi
Journal:  Childs Nerv Syst       Date:  2006-07-05       Impact factor: 1.475

  1 in total

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