BACKGROUND: Sulcate plantare keratolysis or pitted keratolysis (plantar keratolysis sulcatum) is a disease that is commonly found in tropical countries. Patients have also reported plantar hyperhidrosis. OBJECTIVE: Two patients with pitted keratolysis resistant to topical and systemic treatments are described. METHODS: Both patients were injected with botulinum toxin distributed evenly through the plantar extension. RESULTS: The response to the treatment was excellent despite using a low dose of botulinum toxin with the plantar keratolysis healing completely. CONCLUSION: Hyperhidrosis may be considered the major etiologic factor for pitted keratolysis that does not respond to treatment.
BACKGROUND:Sulcate plantare keratolysis or pitted keratolysis (plantar keratolysis sulcatum) is a disease that is commonly found in tropical countries. Patients have also reported plantar hyperhidrosis. OBJECTIVE: Two patients with pitted keratolysis resistant to topical and systemic treatments are described. METHODS: Both patients were injected with botulinum toxin distributed evenly through the plantar extension. RESULTS: The response to the treatment was excellent despite using a low dose of botulinum toxin with the plantar keratolysis healing completely. CONCLUSION:Hyperhidrosis may be considered the major etiologic factor for pitted keratolysis that does not respond to treatment.