Literature DB >> 15606732

Thickness of healthy and affected skin of children with port wine stains: potential repercussions on response to pulsed dye laser treatment.

Eduardo Nagore1, Celia Requena, Amparo Sevila, Joaquim Coll, Dolors Costa, Rafael Botella-Estrada, Onofre Sanmartin, Carlos Serra-Guillén, Carlos Guillén.   

Abstract

BACKGROUND: Response of port wine stain to pulsed dye laser therapy is variable and dependent on treatment settings used and anatomic site as well as on size and depth of ectatic vessels.
OBJECTIVE: Our purpose was to evaluate skin thickness in different anatomic areas and in port wine stain to thus assess its possible role in the response to pulsed dye laser.
MATERIALS AND METHODS: Twenty-one children with port wine stain underwent high-frequency ultrasound evaluation (20 MHz). Eighteen unaffected areas were considered in each patient and an additional measure was taken from the symmetric affected skin when present (50 areas).
RESULTS: Skin was thicker in the centrofacial area, dermatome V1 (followed by dermatome V2, dermatome V3, and dermatomes C1-2), and with increasing age. No substantial difference between affected and symmetric nonaffected skin was found.
CONCLUSION: Thicker cutaneous areas fit with those that typically respond worse to pulsed dye laser. Differences in skin thickness related to age support the fact that better responses are achieved in younger patients.

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Year:  2004        PMID: 15606732     DOI: 10.1111/j.1524-4725.2004.30503.x

Source DB:  PubMed          Journal:  Dermatol Surg        ISSN: 1076-0512            Impact factor:   3.398


  4 in total

Review 1.  Laser and IPL treatment of port-wine stains: therapy options, limitations, and practical aspects.

Authors:  Annette Klein; Wolfgang Bäumler; Michael Landthaler; Philipp Babilas
Journal:  Lasers Med Sci       Date:  2011-03-10       Impact factor: 3.161

2.  [Potential and limitations of dye laser therapy for capillary malformations].

Authors:  A Klein; U Hohenleutner
Journal:  HNO       Date:  2014-01       Impact factor: 1.284

Review 3.  Extracranial vascular malformations (hemangiomas and vascular malformations) in children and adolescents - diagnosis, clinic, and therapy.

Authors:  Behfar Eivazi; Jochen A Werner
Journal:  GMS Curr Top Otorhinolaryngol Head Neck Surg       Date:  2014-12-01

4.  Therapeutic effect of high-frequency ultrasound-assisted dye laser on hemangioma and its influence on serum HIF-1α in patients.

Authors:  Hongzhang Hu; Pengyuan Song; Jinyan Yang; Xia Wang; Zhaohui Chen; Jianhua Fang
Journal:  J Clin Lab Anal       Date:  2019-09-30       Impact factor: 2.352

  4 in total

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