Literature DB >> 15606639

Synergic in-vitro activity of imipenem and sulbactam against Acinetobacter baumannii.

J Y Choi1, Y Soo Park, C H Cho, Y Seon Park, S Y Shin, Y G Song, D Yong, K Lee, J M Kim.   

Abstract

The interaction between sulbactam and imipenem was evaluated with four clinical isolates of Acinetobacter baumannii, including two isolates resistant to imipenem, one of which produced IMP-1 metallo-beta-lactamase. Two isolates (one of which was imipenem-resistant) were sulbactam-resistant by undefined mechanisms. MICs were determined by standard broth microdilution methods. Time-kill assays with imipenem and sulbactam, alone or in combination at 0.5 x MIC and 1 x MIC, showed a synergic effect in all four isolates of A. baumannii after incubation for 0, 4, 8 and > 24 h at 35 degrees C.

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Year:  2004        PMID: 15606639     DOI: 10.1111/j.1469-0691.2004.00987.x

Source DB:  PubMed          Journal:  Clin Microbiol Infect        ISSN: 1198-743X            Impact factor:   8.067


  10 in total

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Authors:  Federico Perez; Andrea M Hujer; Kristine M Hujer; Brooke K Decker; Philip N Rather; Robert A Bonomo
Journal:  Antimicrob Agents Chemother       Date:  2007-07-23       Impact factor: 5.191

2.  Tetracycline tethered to titanium inhibits colonization by Gram-negative bacteria.

Authors:  Helen Davidson; Martin Poon; Ray Saunders; Irving M Shapiro; Noreen J Hickok; Christopher S Adams
Journal:  J Biomed Mater Res B Appl Biomater       Date:  2014-11-12       Impact factor: 3.368

Review 3.  In search for a synergistic combination against pandrug-resistant A. baumannii; methodological considerations.

Authors:  Stamatis Karakonstantis; Petros Ioannou; Diamantis D Kofteridis
Journal:  Infection       Date:  2022-01-04       Impact factor: 3.553

Review 4.  Acinetobacter baumannii: emergence of a successful pathogen.

Authors:  Anton Y Peleg; Harald Seifert; David L Paterson
Journal:  Clin Microbiol Rev       Date:  2008-07       Impact factor: 26.132

Review 5.  Ampicillin/sulbactam: current status in severe bacterial infections.

Authors:  Petros I Rafailidis; Eleni N Ioannidou; Matthew E Falagas
Journal:  Drugs       Date:  2007       Impact factor: 9.546

6.  In vitro responses of Acinetobacter baumannii to two- and three-drug combinations following exposure to colistin and doripenem.

Authors:  Louise M Oleksiuk; M Hong Nguyen; Ellen G Press; Cassaundra L Updike; Jessica A O'Hara; Yohei Doi; Cornelius J Clancy; Ryan K Shields
Journal:  Antimicrob Agents Chemother       Date:  2013-11-18       Impact factor: 5.191

7.  A macromolecular approach to eradicate multidrug resistant bacterial infections while mitigating drug resistance onset.

Authors:  Willy Chin; Guansheng Zhong; Qinqin Pu; Chuan Yang; Weiyang Lou; Paola Florez De Sessions; Balamurugan Periaswamy; Ashlynn Lee; Zhen Chang Liang; Xin Ding; Shujun Gao; Collins Wenhan Chu; Simone Bianco; Chang Bao; Yen Wah Tong; Weimin Fan; Min Wu; James L Hedrick; Yi Yan Yang
Journal:  Nat Commun       Date:  2018-03-02       Impact factor: 14.919

8.  Sulbactam Enhances in vitro Activity of β-Lactam Antibiotics Against Acinetobacter baumannii.

Authors:  Leilei Wang; Yuancheng Chen; Renru Han; Zhiwei Huang; Xuefei Zhang; Fupin Hu; Fan Yang
Journal:  Infect Drug Resist       Date:  2021-09-28       Impact factor: 4.003

9.  Epidemiology, clinical characteristics and outcomes of extensively drug-resistant Acinetobacter baumannii infections among solid organ transplant recipients.

Authors:  Ryan K Shields; Cornelius J Clancy; Louise M Gillis; Eun J Kwak; Fernanda P Silveira; Rima C Abdel Massih; Gregory A Eschenauer; Brian A Potoski; M Hong Nguyen
Journal:  PLoS One       Date:  2012-12-20       Impact factor: 3.240

10.  In Vitro Synergistic Effects of Antimicrobial Combinations on Extensively Drug-Resistant Pseudomonas aeruginosa and Acinetobacter baumannii Isolates.

Authors:  Hyukmin Lee; Kyung Ho Roh; Seong Geun Hong; Hee Bong Shin; Seok Hoon Jeong; Wonkeun Song; Young Uh; Dongeun Yong; Kyungwon Lee
Journal:  Ann Lab Med       Date:  2016-03       Impact factor: 3.464

  10 in total

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