Literature DB >> 15606108

Asymmetric synthesis of the AB ring system of lactonamycin.

T Ross Kelly1, Xiaolu Cai, Bin Tu, Eric L Elliott, Gilles Grossmann, Pierre Laurent.   

Abstract

[reaction: see text] An enantiospecific synthesis of the AB fragment of lactonamycin (5) is achieved in eight steps from dimethyl D-tartrate. Ester enolate chemistry features prominently in the sequence.

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Year:  2004        PMID： 15606108     DOI： 10.1021/ol047922h

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  2 in total

1.  Investigations Concerning the Syntheses of TADDOL-Derived Secondary Amines and Their Use To Access Novel Chiral Organocatalysts.

Authors:  Katharina Gratzer; Mario Waser
Journal:  Synthesis (Stuttg)       Date:  2012-12       Impact factor: 3.157

2.  Alkylation of lithiated dimethyl tartrate acetonide with unactivated alkyl halides and application to an asymmetric synthesis of the 2,8-dioxabicyclo[3.2.1]octane core of squalestatins/zaragozic acids.

Authors:  Herman O Sintim; Hamad H Al Mamari; Hasanain A A Almohseni; Younes Fegheh-Hassanpour; David M Hodgson
Journal:  Beilstein J Org Chem       Date:  2019-05-31       Impact factor: 2.883
  2 in total

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