Four-point electrode measurement of impedance in the vicinity of bovine aorta for quasi-static frequencies.

Results are presented here of experimental measurements using a four-point electrode technique to measure the complex impedance of bovine aorta submerged in Ringer's solution. Impedance measurements were taken at 250 microm intervals, ranging from 0 (the electrode directly on the surface of the tissue) to 10 mm. Frequencies ranged from 1 kHz to 10 MHz. Throughout this range, the measured impedance changed by an average of 400% when the electrode was 10 mm from the tissue as compared to when the electrode was in direct contact with the tissue. The change in impedance made it possible to determine when the electrode made contact with the arterial wall. 2004 Wiley-Liss, Inc.