Literature DB >> 15605071

The epidemiology of respiratory failure in neonates born at an estimated gestational age of 34 weeks or more.

Reese H Clark1.   

Abstract

OBJECTIVE: To prospectively evaluate the primary causes for the use of mechanical ventilation in near-term neonates and to determine the rates of death, chronic lung disease, and neurological complications in these infants. STUDY
DESIGN: We collected data on 1011 neonates who were > or =34 weeks' estimated gestational age; intubated within 72 hours of birth; and expected to require ventilation for more than 6 hours.
RESULTS: The study population had a mean estimated gestational age of 37+/-2 weeks; had a mean birth weight of 2.9+/-0.6 kg; and were predominantly male (62%), white (69%), and delivered by cesarean section (55%). Respiratory distress syndrome (n=437) was the most common pulmonary illness. Chronic lung disease was diagnosed in 109 (11%); neurological complications were reported in 86 (9%); and 51 (5%) patients died.
CONCLUSIONS: Neonates > or =34 weeks who require mechanical ventilation represent a high-risk population who have significant morbidity and mortality.

Entities:  

Mesh:

Year:  2005        PMID: 15605071     DOI: 10.1038/sj.jp.7211242

Source DB:  PubMed          Journal:  J Perinatol        ISSN: 0743-8346            Impact factor:   2.521


  32 in total

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