Literature DB >> 1560466

Crystallization and preliminary X-ray diffraction studies of a protective cloned 28 kDa glutathione S-transferase from Schistosoma mansoni.

F Trottein1, M C Vaney, B Bachet, R J Pierce, N Colloc'h, J P Lecocq, A Capron, J P Mornon.   

Abstract

Crystals of the recombinant 28 kDa glutathione S-transferase from Schistosoma mansoni have been obtained by the hanging-drop method of vapor diffusion from ammonium sulfate solutions. The successful crystallization of this enzyme required the presence of a reducing agent and S-hexylglutathione. The crystals belong to the cubic space group P4(1)32 (or P4(3)32), with unit cell dimensions a = 122.6 A and contain one molecule in the asymmetric unit. The crystals diffract to at least 2.8 A resolution and are suitable for X-ray crystallographic structure analysis.

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Year:  1992        PMID： 1560466     DOI： 10.1016/0022-2836(92)91013-f

Source DB:  PubMed          Journal:  J Mol Biol        ISSN： 0022-2836            Impact factor:   5.469


  7 in total

1.  Induction of mucosal immune responses against a heterologous antigen fused to filamentous hemagglutinin after intranasal immunization with recombinant Bordetella pertussis.

Authors:  G Renauld-Mongénie; N Mielcarek; J Cornette; A M Schacht; A Capron; G Riveau; C Locht
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-23       Impact factor: 11.205

Review 2.  The redox biology of schistosome parasites and applications for drug development.

Authors:  Hsin-Hung Huang; Coraline Rigouin; David L Williams
Journal:  Curr Pharm Des       Date:  2012       Impact factor: 3.116

3.  Intranasal priming with recombinant Bordetella pertussis for the induction of a systemic immune response against a heterologous antigen.

Authors:  N Mielcarek; J Cornette; A M Schacht; R J Pierce; C Locht; A Capron; G Riveau
Journal:  Infect Immun       Date:  1997-02       Impact factor: 3.441

4.  Bordetella pertussis filamentous hemagglutinin enhances the immunogenicity of liposome-delivered antigen administered intranasally.

Authors:  O Poulain-Godefroy; N Mielcarek; N Ivanoff; F Remoué; A M Schacht; N Phillips; C Locht; A Capron; G Riveau
Journal:  Infect Immun       Date:  1998-04       Impact factor: 3.441

5.  Safety and immunogenicity of rSh28GST antigen in humans: phase 1 randomized clinical study of a vaccine candidate against urinary schistosomiasis.

Authors:  Gilles Riveau; Dominique Deplanque; Franck Remoué; Anne-Marie Schacht; Hubert Vodougnon; Monique Capron; Michel Thiry; Joseph Martial; Christian Libersa; André Capron
Journal:  PLoS Negl Trop Dis       Date:  2012-07-03

Review 6.  Metazoan Parasite Vaccines: Present Status and Future Prospects.

Authors:  Christian Stutzer; Sabine A Richards; Mariette Ferreira; Samantha Baron; Christine Maritz-Olivier
Journal:  Front Cell Infect Microbiol       Date:  2018-03-13       Impact factor: 5.293

7.  Cytokine responses to the anti-schistosome vaccine candidate antigen glutathione-S-transferase vary with host age and are boosted by praziquantel treatment.

Authors:  Claire D Bourke; Norman Nausch; Nadine Rujeni; Laura J Appleby; François Trottein; Nicholas Midzi; Takafira Mduluza; Francisca Mutapi
Journal:  PLoS Negl Trop Dis       Date:  2014-05-08
  7 in total

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