Literature DB >> 1560434

Analogues of natural phloroglucinols as antagonists against both thromboxane A2 and leukotriene D4.

M Tada1, K Chiba, T Takakuwa, E Kojima.   

Abstract

Antagonists against both thromboxane A2 and leukotriene D4 were prepared from phloroglucinol. These compounds showed almost the same activity as the chinesins which were isolated from Hypericum chinese L. The correlation between the structures and activity was studied in the synthesized and naturally occurring phloroglucinol derivatives.

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Year:  1992        PMID: 1560434     DOI: 10.1021/jm00085a006

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


  3 in total

1.  Polyopes affinis alleviates airway inflammation in a murine model of allergic asthma.

Authors:  Dae-Sung Lee; Won Sun Park; Soo-Jin Heo; Seon-Heui Cha; Daekyung Kim; You-Jin Jeon; Sae-Gwang Park; Su-Kil Seo; Jung Sik Choi; Sung-Jae Park; Eun Bo Shim; Il-Whan Choi; Won-Kyo Jung
Journal:  J Biosci       Date:  2011-12       Impact factor: 1.826

2.  Total Synthesis and Anticancer Activity of (+)-Hypercalin C and Congeners.

Authors:  Yongfeng Tao; Keighley Reisenauer; Joseph H Taube; Daniel Romo
Journal:  Angew Chem Int Ed Engl       Date:  2019-02-01       Impact factor: 15.336

3.  Novel synthesized 2, 4-DAPG analogues: antifungal activity, mechanism and toxicology.

Authors:  Liang Gong; Haibo Tan; Feng Chen; Taotao Li; Jianyu Zhu; Qijie Jian; Debao Yuan; Liangxiong Xu; Wenzhong Hu; Yueming Jiang; Xuewu Duan
Journal:  Sci Rep       Date:  2016-08-26       Impact factor: 4.379

  3 in total

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