| Literature DB >> 15604105 |
S Sri Krishna1, Nick V Grishin.
Abstract
SUMMARY: Along with their mutating sequences, protein structures change in time. Analyzing a formate dehydrogenase domain that is evolutionarily related to ferredoxin, but simultaneously contains all the structural elements of a beta-Grasp fold, we illustrate here a mechanism termed as structural drift, by which changes to a protein fold can occur. CONTACT: grishin@chop.swmed.edu.Mesh:
Substances:
Year: 2004 PMID: 15604105 DOI: 10.1093/bioinformatics/bti227
Source DB: PubMed Journal: Bioinformatics ISSN: 1367-4803 Impact factor: 6.937