AIM: The limitations and opportunities of revised definition of fevers of unknown origin (FUO) in comparison to conventional definition were investigated, and prehospital characteristics of the patients were detailed. METHOD: The patients were grouped according to both revised and classic definitions of FUO. RESULTS: Fifty-nine of the 80 patients (74%) met the conventional definition of FUO. Before their admissions, all patients had at least one course of antibiotic therapy. The aetiology was infectious in 52%, autoimmune in 19%, and neoplastic in 17%. In 12% of the cases, the reason for high fever could not be explained. The most common infectious aetiologies were various forms of tuberculosis (12%), brucellosis (12%), salmonella (7%) and malaria (5%). The revised definition inflated the rate of infectious aetiology. CONCLUSION: A standardized set of diagnostic tools used in this study was suggested. The subjects of FUO series have to be screened for endemic infections.
AIM: The limitations and opportunities of revised definition of fevers of unknown origin (FUO) in comparison to conventional definition were investigated, and prehospital characteristics of the patients were detailed. METHOD: The patients were grouped according to both revised and classic definitions of FUO. RESULTS: Fifty-nine of the 80 patients (74%) met the conventional definition of FUO. Before their admissions, all patients had at least one course of antibiotic therapy. The aetiology was infectious in 52%, autoimmune in 19%, and neoplastic in 17%. In 12% of the cases, the reason for high fever could not be explained. The most common infectious aetiologies were various forms of tuberculosis (12%), brucellosis (12%), salmonella (7%) and malaria (5%). The revised definition inflated the rate of infectious aetiology. CONCLUSION: A standardized set of diagnostic tools used in this study was suggested. The subjects of FUO series have to be screened for endemic infections.
Authors: Chantal P Bleeker-Rovers; Fidel J Vos; Aart H Mudde; Anton S M Dofferhoff; Lioe-Fee de Geus-Oei; Anton J Rijnders; Paul F M Krabbe; Frans H M Corstens; Jos W M van der Meer; Wim J G Oyen Journal: Eur J Nucl Med Mol Imaging Date: 2006-12-14 Impact factor: 9.236
Authors: Rinkesh K Bansal; Narendra S Choudhary; Saurabh K Patle; Amit Agarwal; Gagandeep Kaur; Haimanti Sarin; Rajesh Puri Journal: Indian J Gastroenterol Date: 2018-03-28
Authors: William F Wright; Gayane Yenokyan; Patricia J Simner; Karen C Carroll; Paul G Auwaerter Journal: Open Forum Infect Dis Date: 2022-04-09 Impact factor: 4.423