| Literature DB >> 15602767 |
Solveig Roussel1, Thierry Billard, Bernard R Langlois, Laurent Saint-James.
Abstract
Various trifluoroacetamides and trifluoromethanesulfinamides, derived from chiral silylated amino alcohols, have been synthesized with the goal of achieving enantioselective nucleophilic trifluoromethylation. The best results were obtained with (R)-phenylglycinol derivatives, but the ee values did not exceed 30 %.Entities:
Year: 2005 PMID： 15602767 DOI： 10.1002/chem.200400777
Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236