| Literature DB >> 15599880 |
Mark A Little1, Charles D Pusey.
Abstract
Rapidly progressive glomerulonephritis (RPGN) must be diagnosed and treated quickly to prevent irreversible organ injury. The commonest cause of RPGN is anti-neutrophil cytoplasm antibody (ANCA) associated small vessel vasculitis, and the most severe is anti-glomerular basement membrane (GBM) antibody disease. In this review we address pathogenesis, diagnosis, treatment and outcome in these two entities, with emphasis on novel therapies.Entities:
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Year: 2004 PMID： 15599880
Source DB: PubMed Journal: J Nephrol ISSN： 1121-8428 Impact factor: 3.902