Literature DB >> 15599450

Direct intramolecular arylation of unactivated arenes: application to the synthesis of aporphine alkaloids.

Marc Lafrance1, Nicole Blaquière, Keith Fagnou.   

Abstract

The direct intramolecular C-H arylation of unactivated arenes is a viable strategy for the synthesis of aporphine alkaloids. These reactions occur with 3 to 5 mol% catalyst and generate the aporphine skeleton in up to 99% yield.

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Year:  2004        PMID: 15599450     DOI: 10.1039/b410394g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  7 in total

1.  Identification of C10 nitrogen-containing aporphines with dopamine D1 versus D5 receptor selectivity.

Authors:  Anupam Karki; Reecan Juarez; Hari K Namballa; Ian Alberts; Wayne W Harding
Journal:  Bioorg Med Chem Lett       Date:  2020-02-20       Impact factor: 2.823

2.  Microwave-Assisted Direct Biaryl Coupling: First Application to the Synthesis of Aporphines.

Authors:  Sandeep Chaudhary; Stevan Pecic; Onica Legendre; Wayne W Harding
Journal:  Tetrahedron Lett       Date:  2009-05-20       Impact factor: 2.415

3.  Exclusive 5-exo-dig hydroarylation of o-alkynyl biaryls proceeding via C-H activation pathway.

Authors:  Natalia Chernyak; Vladimir Gevorgyan
Journal:  J Am Chem Soc       Date:  2008-03-22       Impact factor: 15.419

4.  (+/-)-Nantenine analogs as antagonists at human 5-HT(2A) receptors: C1 and flexible congeners.

Authors:  Sandeep Chaudhary; Stevan Pecic; Onica Legendre; Hérnan A Navarro; Wayne W Harding
Journal:  Bioorg Med Chem Lett       Date:  2009-03-16       Impact factor: 2.823

5.  A New Route to Azafluoranthene Natural Products via Direct Arylation.

Authors:  Shashikanth Ponnala; Wayne W Harding
Journal:  European J Org Chem       Date:  2013-01-03

6.  1-(2-Bromobenzoyl)-6,7-(methylene-dioxy)isoquinoline.

Authors:  Supakit Achiwawanich; Nisachon Khunnawutmanotham; Supanna Techasakul; Narongsuk Chaichit; Sutatip Siripaisarnpipat
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-12-11

7.  Synthesis of dihydrophenanthridines by a sequence of Ugi-4CR and palladium-catalyzed intramolecular C-H functionalization.

Authors:  Florence Bonnaterre; Michèle Bois-Choussy; Jieping Zhu
Journal:  Beilstein J Org Chem       Date:  2008-04-08       Impact factor: 2.883

  7 in total

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