Literature DB >> 15598218

A tale of aborigines, conquerors and slaves: Alu insertion polymorphisms and the peopling of Canary Islands.

N Maca-Meyer1, J Villar, L Pérez-Méndez, A Cabrera de León, C Flores.   

Abstract

Classical, mitochondrial DNA (mtDNA) and Y chromosome markers have been used to examine the genetic admixture in present day inhabitants of the Canary Islands. In this study, we report the analysis of ten autosomal Alu insertion polymorphisms in 364 samples from the seven main islands of the Archipelago, and their comparison to continental samples. The detection of population-specific alleles from the Iberian Peninsula and Northwest Africa, as well as their affinities on the basis of genetic distances and principal component analysis, support a clear link between these populations. Coincident with previous results, the Canarian gene pool can be distinguished as being halfway between those of its putative parents, although with a major Iberian contribution (62-78%). Both the substantial Northwest African contribution (23-38%), and the minor sub-Saharan African input (3%), suggest that the genetic legacy from the aborigines and slaves still persists in the Canary Islanders.

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Year:  2004        PMID: 15598218     DOI: 10.1046/j.1529-8817.2003.00125.x

Source DB:  PubMed          Journal:  Ann Hum Genet        ISSN: 0003-4800            Impact factor:   1.670


  8 in total

1.  No association between genetic ancestry and susceptibility to asthma or atopy in Canary Islanders.

Authors:  María Pino-Yanes; Almudena Corrales; José Cumplido; Ruperto González; María José Torres-Galván; Orlando Acosta Fernández; Inmaculada Sánchez-Machín; Javier Figueroa; Anselmo Sánchez-Palacios; Jesús Villar; Mariano Hernández; Teresa Carrillo; Carlos Flores
Journal:  Immunogenetics       Date:  2012-06-19       Impact factor: 2.846

2.  Description of a simple multiplex PCR-SSCP method for AB0 genotyping and its application to the peopling of the Canary Islands.

Authors:  Rosa Fregel; Nicole Maca-Meyer; Vicente Martínez Cabrera; Ana María González; José María Larruga
Journal:  Immunogenetics       Date:  2005-09-29       Impact factor: 2.846

3.  Polymorphic Alu insertions and the genetic structure of Iberian Basques.

Authors:  S García-Obregón; M A Alfonso-Sánchez; A M Pérez-Miranda; M M de Pancorbo; J A Peña
Journal:  J Hum Genet       Date:  2007-02-03       Impact factor: 3.172

4.  Angiotensin-converting enzyme insertion/deletion polymorphism is not associated with susceptibility and outcome in sepsis and acute respiratory distress syndrome.

Authors:  Jesús Villar; Carlos Flores; Lina Pérez-Méndez; Nicole Maca-Meyer; Elena Espinosa; Jesús Blanco; Ruben Sangüesa; Arturo Muriel; Paula Tejera; Mercedes Muros; Arthur S Slutsky
Journal:  Intensive Care Med       Date:  2007-12-05       Impact factor: 17.440

5.  North African influences and potential bias in case-control association studies in the Spanish population.

Authors:  María Pino-Yanes; Almudena Corrales; Santiago Basaldúa; Alexis Hernández; Luisa Guerra; Jesús Villar; Carlos Flores
Journal:  PLoS One       Date:  2011-03-30       Impact factor: 3.240

6.  TNFA-863 polymorphism is associated with a reduced risk of chronic obstructive pulmonary disease: a replication study.

Authors:  Elizabeth Córdoba-Lanús; Rebeca Baz-Dávila; Juan P de-Torres; María C Rodríguez-Pérez; Nicole Maca-Meyer; Nerea Varo; Chaxiraxi Medina-Coello; Armando Aguirre-Jaime; Ciro Casanova
Journal:  BMC Med Genet       Date:  2011-10-10       Impact factor: 2.103

7.  Isolation and prominent aboriginal maternal legacy in the present-day population of La Gomera (Canary Islands).

Authors:  Rosa Fregel; Vicente M Cabrera; José M Larruga; Juan C Hernández; Alejandro Gámez; Jose J Pestano; Matilde Arnay; Ana M González
Journal:  Eur J Hum Genet       Date:  2014-11-19       Impact factor: 4.246

8.  Role of HIF1A, VEGFA and VEGFR2 SNPs in the Susceptibility and Progression of COPD in a Spanish Population.

Authors:  Rebeca Baz-Dávila; Adriana Espinoza-Jiménez; María Del Cristo Rodríguez-Pérez; Javier Zulueta; Nerea Varo; Ángela Montejo; Delia Almeida-González; Armando Aguirre-Jaime; Elizabeth Córdoba-Lanús; Ciro Casanova
Journal:  PLoS One       Date:  2016-05-10       Impact factor: 3.240

  8 in total

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