Literature DB >> 15598066

Factors influencing the length of hospitalisation in intensive care units: a prospective observational study.

Franca Vacca1, Monica Vaiani, Andrea Messori, Sabrina Trippoli, Susanna Maltoni, Filippo Pelaotti, Benedetta Santarlasci, Filippo Bardelli.   

Abstract

INTRODUCTION: The length of stay (LOS) in patients admitted to intensive care units (ICUs) is influenced by the clinical history of the patient, so the main factors affecting clinical outcome are logical candidates to be predictors of LOS. Since there is still limited information about which factors can influence LOS in these patients, we undertook this observational study in Italian hospitals.
MATERIALS AND METHODS: From 1 August to 31 October 2001 we enrolled a maximum of 10 consecutive patients admitted to ICUs in 16 Italian hospitals. The following information was recorded from each patient: date of admission; APACHE II score on admission; active sepsis and/or septic shock on admission; sepsis and/or septic shock developed during the stay in ICU; Glasgow coma scale on the third day; date and clinical outcome upon discharge from the hospital (alive or dead).
RESULTS: In the study 131 patients were enrolled; 31 (23.7%) had active sepsis upon admission to ICU and 10 (7.6%) had septic shock; 12 (9.2%) developed sepsis during hospitalization and 12 (9.2%) developed septic shock. At the end of the study, 101 patients were alive and 30 had died. The overall mean LOS was 12 days. The mean LOS was 18.3 days for the subgroup with sepsis and 8.3 days in the subgroup without sepsis. Sepsis was the only factor that significantly influenced the LOS (P = 0.016).
CONCLUSIONS: Our study was aimed to analyse the factors that influence the LOS in ICU patients and found that among the variables that affected LOS, sepsis had the greatest impact. Other studies had evaluated the impact of some variables on LOS and identified sepsis and infection as a determinant prolonging LOS.

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Year:  2004        PMID: 15598066     DOI: 10.1023/b:phar.0000042880.12835.4e

Source DB:  PubMed          Journal:  Pharm World Sci        ISSN: 0928-1231


  11 in total

1.  Implementation of a clinical practice guideline for stress ulcer prophylaxis increases appropriateness and decreases cost of care.

Authors:  S Pitimana-aree; D Forrest; G Brown; A Anis; X H Wang; P Dodek
Journal:  Intensive Care Med       Date:  1998-03       Impact factor: 17.440

2.  Risk factors and outcome of nosocomial infections: results of a matched case-control study of ICU patients.

Authors:  E Girou; F Stephan; A Novara; M Safar; J Y Fagon
Journal:  Am J Respir Crit Care Med       Date:  1998-04       Impact factor: 21.405

3.  APACHE II: a severity of disease classification system.

Authors:  W A Knaus; E A Draper; D P Wagner; J E Zimmerman
Journal:  Crit Care Med       Date:  1985-10       Impact factor: 7.598

Review 4.  The risk of determining risk with multivariable models.

Authors:  J Concato; A R Feinstein; T R Holford
Journal:  Ann Intern Med       Date:  1993-02-01       Impact factor: 25.391

Review 5.  Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation.

Authors:  E Abraham; M A Matthay; C A Dinarello; J L Vincent; J Cohen; S M Opal; M Glauser; P Parsons; C J Fisher; J E Repine
Journal:  Crit Care Med       Date:  2000-01       Impact factor: 7.598

6.  Bleeding and pneumonia in intensive care patients given ranitidine and sucralfate for prevention of stress ulcer: meta-analysis of randomised controlled trials.

Authors:  A Messori; S Trippoli; M Vaiani; M Gorini; A Corrado
Journal:  BMJ       Date:  2000-11-04

7.  Antithrombin III in patients with severe sepsis. A randomized, placebo-controlled, double-blind multicenter trial plus a meta-analysis on all randomized, placebo-controlled, double-blind trials with antithrombin III in severe sepsis.

Authors:  B Eisele; M Lamy; L G Thijs; H O Keinecke; H P Schuster; F R Matthias; F Fourrier; H Heinrichs; U Delvos
Journal:  Intensive Care Med       Date:  1998-07       Impact factor: 17.440

8.  Nosocomial bloodstream infection in critically ill patients. Excess length of stay, extra costs, and attributable mortality.

Authors:  D Pittet; D Tarara; R P Wenzel
Journal:  JAMA       Date:  1994-05-25       Impact factor: 56.272

9.  Stress ulcer prophylaxis in critically ill patients. Resolving discordant meta-analyses.

Authors:  D J Cook; B K Reeve; G H Guyatt; D K Heyland; L E Griffith; L Buckingham; M Tryba
Journal:  JAMA       Date:  1996 Jan 24-31       Impact factor: 56.272

10.  Nosocomial pneumonia and mortality among patients in intensive care units.

Authors:  J Y Fagon; J Chastre; A Vuagnat; J L Trouillet; A Novara; C Gibert
Journal:  JAMA       Date:  1996-03-20       Impact factor: 56.272

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  2 in total

1.  [Indications and outcome of ventilated patients treated in a neurological intensive care unit].

Authors:  D Steffling; M Ritzka; W Jakob; A Steinbrecher; S Schwab-Malek; B Kaiser; P Hau; S Boy; K Fuchs; U Bogdahn; F Schlachetzki
Journal:  Nervenarzt       Date:  2012-06       Impact factor: 1.214

2.  Inventory of a Neurological Intensive Care Unit: Who Is Treated and How Long?

Authors:  Roland Backhaus; Franz Aigner; Felix Schlachetzki; Dagmar Steffling; Wolfgang Jakob; Andreas Steinbrecher; Bernhard Kaiser; Peter Hau; Sandra Boy; Kornelius Fuchs; Ulrich Bogdahn; Markus Ritzka
Journal:  Neurol Res Int       Date:  2015-06-24
  2 in total

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