Literature DB >> 15597144

Histamine H3-receptor isoforms.

R A Bakker1.   

Abstract

Increasing evidence supports a role for HA as a neurotransmitter and neuromodulator in various brain functions, including emotion, cognition, and feeding. The recent cloning of the histamine H3 receptor allowed for the subsequent cloning of a variety of H3 receptor isoforms from different species as well as the H4 receptor. As a result a wide variety of H3-receptor isoforms are now known that display differential brain expression patterns and signalling properties. These recent discoveries are discussed in view of the growing interest of the H3 receptor as a target for the development of potential therapeutics.

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Year:  2004        PMID： 15597144     DOI： 10.1007/s00011-004-1286-9

Source DB:  PubMed          Journal:  Inflamm Res        ISSN： 1023-3830            Impact factor:   4.575


  7 in total

Review 1.  International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors.

Authors:  Pertti Panula; Paul L Chazot; Marlon Cowart; Ralf Gutzmer; Rob Leurs; Wai L S Liu; Holger Stark; Robin L Thurmond; Helmut L Haas
Journal:  Pharmacol Rev       Date:  2015-07       Impact factor: 25.468

2.  Generation of a homology model of the human histamine H(3) receptor for ligand docking and pharmacophore-based screening.

Authors:  Birgit Schlegel; Christian Laggner; Rene Meier; Thierry Langer; David Schnell; Roland Seifert; Holger Stark; Hans-Dieter Höltje; Wolfgang Sippl
Journal:  J Comput Aided Mol Des       Date:  2007-08-01       Impact factor: 3.686

3.  Histamine excites neurones in the human submucous plexus through activation of H1, H2, H3 and H4 receptors.

Authors:  Eva Breunig; Klaus Michel; Florian Zeller; Stefan Seidl; Claus Werner Hann v Weyhern; Michael Schemann
Journal:  J Physiol       Date:  2007-07-12       Impact factor: 5.182

4.  Inhibition of histamine receptor 3 suppresses glioblastoma tumor growth, invasion, and epithelial-to-mesenchymal transition.

Authors:  Jia-Ji Lin; Tian-Zhi Zhao; Wen-Ke Cai; Yong-Xiang Yang; Chao Sun; Zhuo Zhang; Yu-Qiao Xu; Ting Chang; Zhu-Yi Li
Journal:  Oncotarget       Date:  2015-07-10

Review 5.  QSAR Modeling of Histamine H3R Antagonists/inverse Agonists as Future Drugs for Neurodegenerative Diseases.

Authors:  Michelle Fidelis Correa; Joao Paulo Dos Santos Fernandes
Journal:  Curr Neuropharmacol       Date:  2018       Impact factor: 7.363

6.  Histamine H(3) receptor integrates peripheral inflammatory signals in the neurogenic control of immune responses and autoimmune disease susceptibility.

Authors:  Dimitry N Krementsov; Emma H Wall; Rebecca A Martin; Meenakumari Subramanian; Rajkumar Noubade; Roxana Del Rio; Gary M Mawe; Jeffrey P Bond; Matthew E Poynter; Elizabeth P Blankenhorn; Cory Teuscher
Journal:  PLoS One       Date:  2013-07-22       Impact factor: 3.240

7.  H3 histamine receptor antagonist pitolisant reverses some subchronic disturbances induced by olanzapine in mice.

Authors:  Magdalena Dudek; Kamil Kuder; Marcin Kołaczkowski; Adrian Olczyk; Elżbieta Żmudzka; Aleksandra Rak; Marek Bednarski; Karolina Pytka; Jacek Sapa; Katarzyna Kieć-Kononowicz
Journal:  Metab Brain Dis       Date:  2016-05-24       Impact factor: 3.584
  7 in total

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