Literature DB >> 15596889

Phage display vectors for the in vitro generation of human antibody fragments.

Michael Hust1, Stefan Dübel.   

Abstract

A major source of human antibodies are phage display libraries, which are constructed from various genetic sources. Antibodies are expressed as scFV and Fab antibody fragments using various vector systems. This review offers a comprehensive overview of M13 phage display antibody vectors and discusses their applications.

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Year:  2005        PMID: 15596889     DOI: 10.1385/1-59259-873-0:071

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  11 in total

Review 1.  Ligand-targeted delivery of therapeutic siRNA.

Authors:  Yutaka Ikeda; Kazunari Taira
Journal:  Pharm Res       Date:  2006-08       Impact factor: 4.200

Review 2.  Bacteriophage vehicles for phage display: biology, mechanism, and application.

Authors:  Walead Ebrahimizadeh; Masoumeh Rajabibazl
Journal:  Curr Microbiol       Date:  2014-03-18       Impact factor: 2.188

3.  Isolation and characterization of selective and potent human Fab inhibitors directed to the active-site region of the two-component NS2B-NS3 proteinase of West Nile virus.

Authors:  Sergey A Shiryaev; Ilian A Radichev; Boris I Ratnikov; Alexander E Aleshin; Katarzyna Gawlik; Boguslaw Stec; Christian Frisch; Achim Knappik; Alex Y Strongin
Journal:  Biochem J       Date:  2010-04-14       Impact factor: 3.857

4.  High-affinity, human antibody-like antibody fragment (single-chain variable fragment) neutralizing the lethal factor (LF) of Bacillus anthracis by inhibiting protective antigen-LF complex formation.

Authors:  Thibaut Pelat; Michael Hust; Emmanuelle Laffly; Florence Condemine; Chantal Bottex; Dominique Vidal; Marie-Paule Lefranc; Stefan Dübel; Philippe Thullier
Journal:  Antimicrob Agents Chemother       Date:  2007-05-21       Impact factor: 5.191

Review 5.  Phage display creates innovative applications to combat hepatitis B virus.

Authors:  Wen Siang Tan; Kok Lian Ho
Journal:  World J Gastroenterol       Date:  2014-09-07       Impact factor: 5.742

6.  Therapeutic antibodies: current state and future trends--is a paradigm change coming soon?

Authors:  Dimiter S Dimitrov; James D Marks
Journal:  Methods Mol Biol       Date:  2009

Review 7.  Phage display for the generation of antibodies for proteome research, diagnostics and therapy.

Authors:  Thomas Schirrmann; Torsten Meyer; Mark Schütte; André Frenzel; Michael Hust
Journal:  Molecules       Date:  2011-01-10       Impact factor: 4.411

Review 8.  Oligopeptide m13 phage display in pathogen research.

Authors:  Jonas Kügler; Jonas Zantow; Torsten Meyer; Michael Hust
Journal:  Viruses       Date:  2013-10-16       Impact factor: 5.048

9.  Development of human-like scFv-Fc antibodies neutralizing Botulinum toxin serotype B.

Authors:  Christine Rasetti-Escargueil; Arnaud Avril; Siham Chahboun; Rob Tierney; Nicola Bak; Sebastian Miethe; Christelle Mazuet; Michel R Popoff; Philippe Thullier; Michael Hust; Thibaut Pelat; Dorothea Sesardic
Journal:  MAbs       Date:  2015-09-18       Impact factor: 5.857

10.  Isolation and characterization of malaria PfHRP2 specific VNAR antibody fragments from immunized shark phage display library.

Authors:  Chiuan Herng Leow; Katja Fischer; Chiuan Yee Leow; Katleen Braet; Qin Cheng; James McCarthy
Journal:  Malar J       Date:  2018-10-24       Impact factor: 2.979

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