OBJECTIVE: Many patients with Parkinson's disease (PD) lose weight also early during the disease. The objective of the study was to investigate possible causative factors for this loss. MATERIALS AND METHODS: In this report, 28 PD patients and 28 age- and sex-matched controls were repeatedly assessed with the focus on body weight, body fat mass, dysphagia, olfaction, physical activity, PD symptomatology and drug treatment. RESULTS: Weight loss was seen in PD patients both before and during L-dopa treatment. CONCLUSION: The underlying disease could play a role, but our results also suggest that L-dopa per se could contribute to the weight loss. Blackwell Munksgaard 2004
OBJECTIVE: Many patients with Parkinson's disease (PD) lose weight also early during the disease. The objective of the study was to investigate possible causative factors for this loss. MATERIALS AND METHODS: In this report, 28 PDpatients and 28 age- and sex-matched controls were repeatedly assessed with the focus on body weight, body fat mass, dysphagia, olfaction, physical activity, PD symptomatology and drug treatment. RESULTS:Weight loss was seen in PDpatients both before and during L-dopa treatment. CONCLUSION: The underlying disease could play a role, but our results also suggest that L-dopa per se could contribute to the weight loss. Blackwell Munksgaard 2004
Authors: Roy E Strowd; Michael S Cartwright; Leah V Passmore; Thomas L Ellis; Stephen B Tatter; Mustafa S Siddiqui Journal: J Neurol Date: 2010-03-11 Impact factor: 4.849
Authors: Frauke Adams; Michael Boschmann; Elmar Lobsien; Andreas Kupsch; Axel Lipp; Gabriele Franke; Marie Charlotte Leisse; Juergen Janke; Simone Gottschalk; Joachim Spranger; Jens Jordan Journal: Eur J Clin Pharmacol Date: 2008-07-30 Impact factor: 2.953
Authors: Maria G Cersosimo; Gabriela B Raina; Luis A Pellene; Federico E Micheli; Cristian R Calandra; Ricardo Maiola Journal: Biomed Res Int Date: 2018-07-09 Impact factor: 3.411