PURPOSE: To investigate the short-term physiologic response to three soft lens materials with different oxygen permeability characteristics. METHODS:Forty-three neophytes were randomly prescribed Acuvue 2, Acuvue Advance (Johnson & Johnson Vision Care), or Focus Night & Day (CIBA Vision) for 4 weeks on a daily-wear basis. A further 19 subjects did not wear lenses (control). Experimental and control subjects were examined 2 and 4 weeks after dispensing. Ocular physiologic response was measured with a slitlamp biomicroscope in a strictly masked fashion. RESULTS:Limbal redness increased in the Acuvue 2 group compared with the other two groups. Conjunctival redness increased more in the Acuvue 2 group than in the Acuvue Advance group. More conjunctival staining was seen with the Acuvue Advance and Focus Night & Day groups compared with the Acuvue 2 group. Increased scores for papillary conjunctivitis were seen in the Focus Night & Day group compared with the Acuvue Advance group. CONCLUSIONS: The reduced level of limbal redness seen with the Acuvue Advance and Focus Night & Day groups suggests that these lenses provide more oxygen to the ocular surface than the Acuvue 2 lens to a degree that can be observed clinically. The conjunctival staining response was similar for the Acuvue Advance and Focus Night & Day groups. The results for the Acuvue Advance and Focus Night & Day groups for papillary conjunctivitis may reflect differences in their material and surface properties.
RCT Entities:
PURPOSE: To investigate the short-term physiologic response to three soft lens materials with different oxygen permeability characteristics. METHODS: Forty-three neophytes were randomly prescribed Acuvue 2, Acuvue Advance (Johnson & Johnson Vision Care), or Focus Night & Day (CIBA Vision) for 4 weeks on a daily-wear basis. A further 19 subjects did not wear lenses (control). Experimental and control subjects were examined 2 and 4 weeks after dispensing. Ocular physiologic response was measured with a slitlamp biomicroscope in a strictly masked fashion. RESULTS: Limbal redness increased in the Acuvue 2 group compared with the other two groups. Conjunctival redness increased more in the Acuvue 2 group than in the Acuvue Advance group. More conjunctival staining was seen with the Acuvue Advance and Focus Night & Day groups compared with the Acuvue 2 group. Increased scores for papillary conjunctivitis were seen in the Focus Night & Day group compared with the Acuvue Advance group. CONCLUSIONS: The reduced level of limbal redness seen with the Acuvue Advance and Focus Night & Day groups suggests that these lenses provide more oxygen to the ocular surface than the Acuvue 2 lens to a degree that can be observed clinically. The conjunctival staining response was similar for the Acuvue Advance and Focus Night & Day groups. The results for the Acuvue Advance and Focus Night & Day groups for papillary conjunctivitis may reflect differences in their material and surface properties.
Authors: Ana Tauste; Elena Ronda; Valborg Baste; Magne Bråtveit; Bente E Moen; María-Del-Mar Seguí Crespo Journal: Int Arch Occup Environ Health Date: 2017-12-04 Impact factor: 3.015
Authors: Suzanne M J Fleiszig; Abby R Kroken; Vincent Nieto; Melinda R Grosser; Stephanie J Wan; Matteo M E Metruccio; David J Evans Journal: Prog Retin Eye Res Date: 2019-11-20 Impact factor: 21.198