Robert Dales1. 1. HECSB/SEP/ECB/AHED/AQHER, Ottawa, Health Canada Air Quality-Health Effects Research Section, Health Canada, 275 Slater Street, 7th Floor, Ottawa, Ontario, Canada K1A 0L2. rdales@ohri.ca
Abstract
OBJECTIVE: Days of high ambient carbon dioxide (CO) have been associated with increased hospital admissions for cardiac disease. This study was conducted to determine if daily concentrations of CO and fine particulates (PM2.5) are associated with daily changes in heart rate variability. METHODS: Each of 36 adults with coronary artery disease had personal exposure to PM2.5 and CO measured along with heart rate variability for one 24-hour period each week for up to 10 weeks. RESULTS: Among those not taking beta-receptor blockers, there was a positive association between the standard deviation of the R-to-R intervals and CO (P = 0.02). No effect was found for PM2.5. CONCLUSIONS: Urban exposure to CO may exert a biologic effect on the heart, which may be modified by medications.
OBJECTIVE: Days of high ambient carbon dioxide (CO) have been associated with increased hospital admissions for cardiac disease. This study was conducted to determine if daily concentrations of CO and fine particulates (PM2.5) are associated with daily changes in heart rate variability. METHODS: Each of 36 adults with coronary artery disease had personal exposure to PM2.5 and CO measured along with heart rate variability for one 24-hour period each week for up to 10 weeks. RESULTS: Among those not taking beta-receptor blockers, there was a positive association between the standard deviation of the R-to-R intervals and CO (P = 0.02). No effect was found for PM2.5. CONCLUSIONS: Urban exposure to CO may exert a biologic effect on the heart, which may be modified by medications.
Authors: Petter Ljungman; Tom Bellander; Alexandra Schneider; Susanne Breitner; Francesco Forastiere; Regina Hampel; Thomas Illig; Bénédicte Jacquemin; Klea Katsouyanni; Stephanie von Klot; Wolfgang Koenig; Timo Lanki; Fredrik Nyberg; Juha Pekkanen; Riccardo Pistelli; Christos Pitsavos; Mårten Rosenqvist; Jordi Sunyer; Annette Peters Journal: Environ Health Perspect Date: 2009-04-06 Impact factor: 9.031
Authors: David M Stieb; Robin Shutt; Lisa Kauri; Sarah Mason; Li Chen; Mieczyslaw Szyszkowicz; Nina A Dobbin; Marc Rigden; Branka Jovic; Marie Mulholland; Martin S Green; Ling Liu; Guillaume Pelletier; Scott A Weichenthal; Robert E Dales; Isaac Luginaah Journal: J Occup Environ Med Date: 2017-04 Impact factor: 2.162