Literature DB >> 15591666

A bedside dipstick method to detect Plasmodium falciparum.

Ira Shah1, C T Deshmukh.   

Abstract

We conducted this study to determine efficacy of Parasight-F (an HRP-II antigen dipstick method to detect P. Falciparum) in children. A total of 30 children were enrolled in the age group of 2 months to 12 years whose peripheral smear showed asexual forms of Plasmodium falciparum. All patients were tested for presence of HRP-II antigen of Plasmodium falciparum in their blood by the Parasight-F dipstick test by either an EDTA sample or a finger prick blood sample. The sensitivity of Parasight-F was 83.3 % However, the sensitivity of Parasight-F to detect Plasmodium Falciparum in case of mixed Plasmodium (Vivax + Falciparum) infection was only 25 %. Also, all patients less than 6 months of age had a negative Parasight-F test. Parasitic index, prior treatment with antimalarials or severity of Falciparum malaria have no effect on the sensitivity of Parasight-F test. We conclude that Parasight-F is an effective tool for diagnosis of Plasmoduim falciparum malaria in children.

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Year:  2004        PMID: 15591666

Source DB:  PubMed          Journal:  Indian Pediatr        ISSN: 0019-6061            Impact factor:   1.411


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Review 2.  Rapid diagnostic tests for diagnosing uncomplicated P. falciparum malaria in endemic countries.

Authors:  Katharine Abba; Jonathan J Deeks; Piero Olliaro; Cho-Min Naing; Sally M Jackson; Yemisi Takwoingi; Sarah Donegan; Paul Garner
Journal:  Cochrane Database Syst Rev       Date:  2011-07-06

Review 3.  Rapid diagnostic tests for diagnosing uncomplicated non-falciparum or Plasmodium vivax malaria in endemic countries.

Authors:  Katharine Abba; Amanda J Kirkham; Piero L Olliaro; Jonathan J Deeks; Sarah Donegan; Paul Garner; Yemisi Takwoingi
Journal:  Cochrane Database Syst Rev       Date:  2014-12-18
  3 in total

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