Literature DB >> 15590546

Clinicopathologic case report: scleral buckle associated nontuberculous mycobacterial scleritis.

Jared S Nielsen1, Steven Blatt, Jay I Perlman, Richard G Gieser.   

Abstract

Nontuberculous mycobacterial (NTM) infections have become increasingly important in ophthalmology, particularly with keratorefractive surgery. We report a case of scleral buckle associated NTM scleritis occurring in a 69-year-old male after silicone sponge explant removal. Purulent scleral ulceration with nodule formation persisted despite topical antimicrobial therapy, buckle removal, and surgical debridement. Eventually, tissue biopsy revealed noncasseating granulomas with acid-fast bacilli that were identified in culture as Mycobacterium chelonae. The infection resolved only after administration of systemic antibiotics. NTM are important pathogens in scleral buckle associated scleritis and should be considered in persistent cases. Surgical therapy remains the cornerstone of therapy, but antimicrobials, particularly newer fourth generation fluoroqunilones, may have an important role in treating scleral buckle associated NTM scleritis.

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Year:  2004        PMID: 15590546     DOI: 10.1080/08820530490882517

Source DB:  PubMed          Journal:  Semin Ophthalmol        ISSN: 0882-0538            Impact factor:   1.975


  6 in total

Review 1.  Pharmacotherapy of scleritis: current paradigms and future directions.

Authors:  Robert M Beardsley; Eric B Suhler; James T Rosenbaum; Phoebe Lin
Journal:  Expert Opin Pharmacother       Date:  2013-02-21       Impact factor: 3.889

2.  Review of moxifloxacin hydrochloride ophthalmic solution in the treatment of bacterial eye infections.

Authors:  Darlene Miller
Journal:  Clin Ophthalmol       Date:  2008-03

Review 3.  Nontuberculous Mycobacterial Ocular Infections: A Systematic Review of the Literature.

Authors:  Wajiha J Kheir; Huda Sheheitli; Maamoun Abdul Fattah; Rola N Hamam
Journal:  Biomed Res Int       Date:  2015-05-27       Impact factor: 3.411

4.  Orbital cellulitis following silicone-sponge scleral buckles.

Authors:  Arie Y Nemet; Joseph R Ferencz; Ori Segal; Amit Meshi
Journal:  Clin Ophthalmol       Date:  2013-10-31

5.  Scleral buckle induce orbital cellulitis and scleritis - A case report and literature review.

Authors:  Reem Alanazi; Silvana Schellini; Osama AlSheikh; Sahar Elkhamary
Journal:  Saudi J Ophthalmol       Date:  2019-01-25

Review 6.  Mycobacterium haemophilum scleritis: two case reports and review of literature.

Authors:  Punyanuch Pisitpayat; Tasanee Sirikul; Poonpilas Hongmanee; Pitak Santanirand; Kaevalin Lekhanont
Journal:  BMC Ophthalmol       Date:  2020-09-23       Impact factor: 2.209

  6 in total

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