| Literature DB >> 15590062 |
Katiuscia Bianchi1, Alessandro Rimessi, Andrea Prandini, György Szabadkai, Rosario Rizzuto.
Abstract
Mitochondria promptly respond to Ca(2+)-mediated cell stimulations with a rapid accumulation of the cation into the matrix. In this article, we review (i) the basic principles of mitochondrial Ca(2+) transport, (ii) the physiological/pathological role of mitochondrial Ca(2+) uptake, (iii) the regulatory mechanisms that may operate in vivo, and (iv) the new targeted Ca(2+) probes that allowed the "rediscovery" of these organelles in calcium signalling.Entities:
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Year: 2004 PMID： 15590062 DOI： 10.1016/j.bbamcr.2004.09.015
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002