BACKGROUND: Granulosa cell tumors (GCTs) of the ovary are rare, hormonally active neoplasms characterized by endocrine manifestations, an indolent course, and late relapse. CASE: We report a case of a prolonged history of ovarian GCT managed primarily with repeat surgical resections. CONCLUSION: This case illustrates the benefits of cytoreductive surgery for the management of recurrent disease, the use of serum tumor markers to help guide therapy, and the importance of extended follow-up.
BACKGROUND:Granulosa cell tumors (GCTs) of the ovary are rare, hormonally active neoplasms characterized by endocrine manifestations, an indolent course, and late relapse. CASE: We report a case of a prolonged history of ovarian GCT managed primarily with repeat surgical resections. CONCLUSION: This case illustrates the benefits of cytoreductive surgery for the management of recurrent disease, the use of serum tumor markers to help guide therapy, and the importance of extended follow-up.
Authors: David Fu; Xiangmin Lv; Guohua Hua; Chunbo He; Jixin Dong; Subodh M Lele; David Wan-Cheng Li; Qiongli Zhai; John S Davis; Cheng Wang Journal: Endocr Relat Cancer Date: 2014-03-04 Impact factor: 5.678
Authors: D Larizza; V Calcaterra; P Sampaolo; G Lanati; P Brambilla; T Mondello; S Cesari Journal: J Endocrinol Invest Date: 2006 Jul-Aug Impact factor: 4.256
Authors: Cheng Wang; Xiangmin Lv; Chao Jiang; Crystal M Cordes; Lan Fu; Subodh M Lele; John S Davis Journal: PLoS One Date: 2012-11-14 Impact factor: 3.240