Literature DB >> 15588677

Inhibition of fowlpox virus by an aqueous acetone extract from galls of Guiera senegalensis J. F. Gmel (Combretaceae).

Charles E Lamien1, Aline Meda, Janet Mans, Marco Romito, Odile G Nacoulma, Gerrit J Viljoen.   

Abstract

An aqueous acetone extract from the galls of Guiera senegalensis was screened for in vitro antiviral activity against fowlpox virus (FPV). Cytopathic effect (CPE) inhibition and plaque inhibition assays were used to show presence of antiviral effects against FPV, whilst cytotoxicity assays established the relative safety of the extract for cells in vitro. Phytochemical analyses revealed the presence of phenolic compounds including flavonoids, tannins and anthocyanins as well as steroids and alkaloids. Thin-layer chromatographical (TLC) analysis also revealed the presence of quercitrin, quercetin, kaempferol, apigenin, rutin, gallic acid as well as unknown flavonoids and unknown phenolic acids. The antiviral effect of the extract was partially attributed to phenolic components including flavonoids.

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Year:  2005        PMID： 15588677     DOI： 10.1016/j.jep.2004.09.016

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  5 in total

1.  Quantitative analysis of rutin, quercetin, naringenin, and gallic acid by validated RP- and NP-HPTLC methods for quality control of anti-HBV active extract of Guiera senegalensis.

Authors:  Perwez Alam; Mohammad K Parvez; Ahmed H Arbab; Mohammed S Al-Dosari
Journal:  Pharm Biol       Date:  2017-12       Impact factor: 3.503

Review 2.  Evaluation of antiviral activities of Houttuynia cordata Thunb. extract, quercetin, quercetrin and cinanserin on murine coronavirus and dengue virus infection.

Authors:  K H Chiow; M C Phoon; Thomas Putti; Benny K H Tan; Vincent T Chow
Journal:  Asian Pac J Trop Med       Date:  2015-12-19       Impact factor: 1.226

3.  Metabolomic-based study of the leafy gall, the ecological niche of the phytopathogen Rhodococcus fascians, as a potential source of bioactive compounds.

Authors:  Aminata P Nacoulma; Olivier M Vandeputte; Manuella De Lorenzi; Mondher El Jaziri; Pierre Duez
Journal:  Int J Mol Sci       Date:  2013-06-14       Impact factor: 5.923

4.  Analysis of antioxidative and antiviral biomarkers β-amyrin, β-sitosterol, lupeol, ursolic acid in Guiera senegalensis leaves extract by validated HPTLC methods.

Authors:  Mohammad K Parvez; Perwez Alam; Ahmed H Arbab; Mohammed S Al-Dosari; Tawfeq A Alhowiriny; Saleh I Alqasoumi
Journal:  Saudi Pharm J       Date:  2018-02-09       Impact factor: 4.330

5.  Transmission blocking activity of Azadirachta indica and Guiera senegalensis extracts on the sporogonic development of Plasmodium falciparum field isolates in Anopheles coluzzii mosquitoes.

Authors:  Rakiswendé S Yerbanga; Leonardo Lucantoni; Robert K Ouédraogo; Dari F Da; Franck A Yao; Koudraogo B Yaméogo; Thomas S Churcher; Giulio Lupidi; Orazio Taglialatela-Scafati; Louis Clément Gouagna; Anna Cohuet; George K Christophides; Jean Bosco Ouédraogo; Annette Habluetzel
Journal:  Parasit Vectors       Date:  2014-04-15       Impact factor: 3.876
  5 in total

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